Strain |
Pseudomonas aeruginosa PAO1 (Stover et al., 2000)
GCF_000006765.1|latest |
Locus Tag |
PA1163
|
Name |
ndvB
Synonym: ndvB |
Replicon | chromosome |
Genomic location | 1260557 - 1263166 (- strand) |
Transposon Mutants | 5 transposon mutants in PAO1 |
Transposon Mutants in orthologs | 7 transposon mutants in orthologs |
Comment | required for the synthesis of periplasmic glucans, and involved in biofilm-specific resistance to a subset of antibiotics |
RefSeq | NP_249854.1 |
GI | 15596360 |
Affymetrix | PA1163_at |
Entrez | 877810 |
GenBank | AAG04552.1 |
INSDC | AAG04552.1 |
NCBI Locus Tag | PA1163 |
protein_id(GenBank) | gb|AAG04552.1|AE004546_7|gnl|PseudoCAP|PA1163 |
TIGR | NTL03PA01164 |
UniParc | UPI00000C5281 |
UniProtKB Acc | Q9I4H4 |
UniProtKB ID | Q9I4H4_PSEAE |
UniRef100 | UniRef100_Q9I4H4 |
UniRef50 | UniRef50_Q9I4H4 |
UniRef90 | UniRef90_Q9I4H4 |
Feature Type | CDS |
Coding Frame | 1 |
Product Name |
NdvB
|
Synonyms | |
Evidence for Translation |
Identified using nanoflow high-pressure liquid chromatography (HPLC) in conjunction with microelectrospray ionization on LTQ XL mass spectrometer (PMID:24291602).
|
Charge (pH 7) | 13.66 |
Kyte-Doolittle Hydrophobicity Value | 0.162 |
Molecular Weight (kDa) | 97.0 |
Isoelectric Point (pI) | 9.14 |
Individual Mappings | |
Additional evidence for subcellular localization |
Results |
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 379 genera
|
Pseudomonas Ortholog Database | View orthologs at Pseudomonas Ortholog Database |
Pseudomonas Ortholog Group |
POG000682 (2121 members) |
Putative Inparalogs | None Found |
STRING database | Search for predicted protein-protein interactions using:
Search term: PA1163
Search term: ndvB
Search term: NdvB
|
Genome-wide identification of Pseudomonas aeruginosa exported proteins using a consensus computational strategy combined with a laboratory-based PhoA fusion screen.
Lewenza S, Gardy JL, Brinkman FS, Hancock RE
Genome Res 2005 Feb;15(2):321-9
PubMed ID: 15687295
|
A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance.
Mah TF, Pitts B, Pellock B, Walker GC, Stewart PS, O'Toole GA
Nature 2003 Nov 20;426(6964):306-10
PubMed ID: 14628055
|
High-level antibiotic resistance in Pseudomonas aeruginosa biofilm: the ndvB gene is involved in the production of highly glycerol-phosphorylated beta-(1->3)-glucans, which bind aminoglycosides.
Sadovskaya I, Vinogradov E, Li J, Hachani A, Kowalska K, Filloux A
Glycobiology 2010 Jul;20(7):895-904
PubMed ID: 20348539
|