Pseudomonas aeruginosa PAO1, PA3638

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016879 ligase activity, forming carbon-nitrogen bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01992
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF09179
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01992
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01992
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0008033 tRNA processing
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd01992
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Hypothetical, unclassified, unknown Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF11734 TilS substrate C-terminal domain IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal 364 432 9.0E-16
Pfam PF09179 TilS substrate binding domain IPR015262 tRNA(Ile)-lysidine synthase, substrate-binding domain 260 323 5.1E-13
PANTHER PTHR43033 TRNA(ILE)-LYSIDINE SYNTHASE-RELATED IPR012094 tRNA(Ile)-lysidine synthase 24 276 2.0E-63
Gene3D G3DSA:1.20.59.20 - - - 237 325 4.5E-12
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 16 233 2.4E-76
SMART SM00977 TilS_C_a_2_a IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal 364 432 2.1E-19
NCBIfam TIGR02432 JCVI: tRNA lysidine(34) synthetase TilS IPR012795 tRNA(Ile)-lysidine synthase, N-terminal 24 203 2.8E-51
SUPERFAMILY SSF82829 MesJ substrate recognition domain-like - - 248 328 3.4E-17
SUPERFAMILY SSF52402 Adenine nucleotide alpha hydrolases-like - - 17 232 7.28E-62
SUPERFAMILY SSF56037 PheT/TilS domain - - 337 434 1.15E-18
NCBIfam TIGR02433 JCVI: tRNA lysidine(34) synthetase TilS C-terminal domain IPR012796 Lysidine-tRNA(Ile) synthetase, C-terminal 364 409 7.1E-14
Hamap MF_01161 tRNA(Ile)-lysidine synthase [tilS]. IPR012094 tRNA(Ile)-lysidine synthase 7 396 23.098185
CDD cd01992 PP-ATPase IPR012795 tRNA(Ile)-lysidine synthase, N-terminal 23 203 1.73327E-76
Pfam PF01171 PP-loop family IPR011063 tRNA(Ile)-lysidine/2-thiocytidine synthase, N-terminal 23 199 2.5E-59

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.