Pseudomonas aeruginosa PAO1, PA3645 (fabZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0009276 Gram-negative-bacterium-type cell wall
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0044255 cellular lipid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 8805534 Reviewed by curator
Biological Process GO:0006633 fatty acid biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 8805534 Reviewed by curator
Molecular Function GO:0016836 hydro-lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01750
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006633 fatty acid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01750
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Fatty acid and phospholipid metabolism Other PAO1 genes in this class
Cell wall / LPS / capsule Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01212 Fatty acid metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00061 Fatty acid biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Lipopolysaccharide biosynthesis ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00780 Biotin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.10.129.10:FF:000001 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ - - 1 146 3.3E-66
NCBIfam TIGR01750 JCVI: 3-hydroxyacyl-ACP dehydratase FabZ IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 142 1.6E-64
Pfam PF07977 FabA-like domain IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ 11 137 3.8E-38
Gene3D G3DSA:3.10.129.10 Hotdog Thioesterase - - 3 146 4.4E-61
Hamap MF_00406 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ [fabZ]. IPR010084 Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ 2 145 36.124706
PANTHER PTHR30272 3-HYDROXYACYL-[ACYL-CARRIER-PROTEIN] DEHYDRATASE IPR013114 Beta-hydroxydecanoyl thiol ester dehydrase, FabA/FabZ 1 143 3.5E-54
CDD cd01288 FabZ - - 11 142 1.30998E-78
SUPERFAMILY SSF54637 Thioesterase/thiol ester dehydrase-isomerase IPR029069 HotDog domain superfamily 1 142 3.67E-53

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.