Pseudomonas aeruginosa PAO1, PA4051 (thiL)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0009030 thiamine-phosphate kinase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 9188462 Reviewed by curator
Biological Process GO:0051188 obsolete cofactor biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0009030 thiamine-phosphate kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02128
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009228 thiamine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02128
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc THISYN-PWY superpathway of thiamin diphosphate biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc PWY-6894 thiamin diphosphate biosynthesis I (E. coli) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Thiamine metabolism ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00730 Thiamine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00586 AIR synthase related protein, N-terminal domain IPR016188 PurM-like, N-terminal domain 29 138 3.5E-25
CDD cd02194 ThiL IPR006283 Thiamine-monophosphate kinase-like 2 292 9.14679E-109
PANTHER PTHR30270 THIAMINE-MONOPHOSPHATE KINASE IPR006283 Thiamine-monophosphate kinase-like 2 319 1.5E-75
Gene3D G3DSA:3.30.1330.10 - IPR036921 PurM-like, N-terminal domain superfamily 1 144 2.9E-48
Hamap MF_02128 Thiamine-monophosphate kinase [thiL]. IPR006283 Thiamine-monophosphate kinase-like 1 317 27.013096
SUPERFAMILY SSF56042 PurM C-terminal domain-like IPR036676 PurM-like, C-terminal domain superfamily 143 303 6.49E-35
Gene3D G3DSA:3.90.650.10 - IPR036676 PurM-like, C-terminal domain superfamily 145 317 4.8E-45
PIRSF PIRSF005303 Thiam_monoph_kin IPR006283 Thiamine-monophosphate kinase-like 1 317 5.2E-78
NCBIfam TIGR01379 JCVI: thiamine-phosphate kinase IPR006283 Thiamine-monophosphate kinase-like 2 317 1.8E-94
SUPERFAMILY SSF55326 PurM N-terminal domain-like IPR036921 PurM-like, N-terminal domain superfamily 1 138 2.09E-34
Pfam PF02769 AIR synthase related protein, C-terminal domain IPR010918 PurM-like, C-terminal domain 150 297 3.6E-6

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.