Pseudomonas aeruginosa UCBPP-PA14, PA14_05530 (mexA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009405 pathogenesis
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 9989496 Reviewed by curator
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00529
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0022857 transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01730
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Transport of small molecules Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01503 Cationic antimicrobial peptide (CAMP) resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01501 beta-Lactam resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SUPERFAMILY SSF111369 HlyD-like secretion proteins - - 49 285 3.79E-94
FunFam G3DSA:2.40.30.170:FF:000001 Multidrug resistance efflux transporter MdtE - - 188 269 8.2E-38
PANTHER PTHR30158 ACRA/E-RELATED COMPONENT OF DRUG EFFLUX TRANSPORTER - - 10 373 2.7E-124
Pfam PF00529 Cation efflux system protein CusB domain 1 IPR043602 Cation efflux system protein CusB, domain 1 279 346 1.3E-8
Gene3D G3DSA:2.40.420.20 - - - 269 362 5.3E-23
Pfam PF16576 Barrel-sandwich domain of CusB or HlyD membrane-fusion IPR032317 RND efflux pump, membrane fusion protein, barrel-sandwich domain 59 278 6.7E-16
Coils Coil Coil - - 103 123 -
FunFam G3DSA:2.40.420.20:FF:000001 Efflux RND transporter periplasmic adaptor subunit - - 269 361 2.0E-31
Gene3D G3DSA:2.40.30.170 - - - 56 268 2.9E-64
NCBIfam TIGR01730 JCVI: efflux RND transporter periplasmic adaptor subunit IPR006143 RND efflux pump, membrane fusion protein 38 360 1.6E-76
Gene3D G3DSA:2.40.50.100 - - - 62 192 2.9E-64
Gene3D G3DSA:1.10.287.470 Helix hairpin bin - - 97 156 2.9E-64

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.