Pseudomonas aeruginosa UCBPP-PA14, PA14_11000 (hpaA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016712 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02310
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0010124 phenylacetate catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02310
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF56645
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0050660 flavin adenine dinucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR02310
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01220 Degradation of aromatic compounds 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00350 Tyrosine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
MetaCyc aromatic biogenic amine degradation (bacteria) InterPro 5.36-75.0 ECO:0000259
match to InterPro signature evidence used in automatic assertion
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PIRSF PIRSF000331 HpaA_HpaB IPR004925 HpaB/PvcC/4-BUDH 11 501 0.0
FunFam G3DSA:1.10.3140.10:FF:000001 4-hydroxyphenylacetate 3-monooxygenase oxygenase component - - 13 151 6.7E-76
Gene3D G3DSA:1.20.140.10 - - - 284 500 1.3E-71
PIRSF PIRSF500125 4_HPA_large IPR024677 4-HPA 3-monooxygenase large component/Pyoverdin chromophore biosynthetic protein 1 518 0.0
Pfam PF03241 4-hydroxyphenylacetate 3-hydroxylase C terminal IPR024719 HpaB/PvcC/4-BUDH C-terminal 288 481 1.8E-58
Gene3D G3DSA:2.40.110.10 - IPR046373 Acyl-CoA oxidase/dehydrogenase, middle domain superfamily 156 282 8.7E-41
SUPERFAMILY SSF47203 Acyl-CoA dehydrogenase C-terminal domain-like IPR036250 Acyl-CoA dehydrogenase-like, C-terminal 272 494 6.91E-45
FunFam G3DSA:1.20.140.10:FF:000044 4-hydroxyphenylacetate 3-monooxygenase oxygenase component - - 284 500 4.0E-106
Pfam PF11794 4-hydroxyphenylacetate 3-hydroxylase N terminal IPR024674 HpaB/PvcC/4-BUDH N-terminal 15 280 5.3E-93
NCBIfam TIGR02310 JCVI: 4-hydroxyphenylacetate 3-monooxygenase, oxygenase component IPR012688 4-hydroxyphenylacetate 3-monooxygenase oxygenase component, gammaproteobacteria 2 520 0.0
Gene3D G3DSA:1.10.3140.10 - - - 14 155 1.1E-49
FunFam G3DSA:2.40.110.10:FF:000026 4-hydroxyphenylacetate 3-monooxygenase oxygenase component - - 152 282 6.0E-70
SUPERFAMILY SSF56645 Acyl-CoA dehydrogenase NM domain-like IPR009100 Acyl-CoA dehydrogenase/oxidase, N-terminal and middle domain superfamily 13 282 1.04E-81
PANTHER PTHR36117 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE-RELATED IPR004925 HpaB/PvcC/4-BUDH 6 514 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.