Pseudomonas aeruginosa UCBPP-PA14, PA14_12200 (holA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003887 DNA-directed DNA polymerase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06144
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006260 DNA replication
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06144
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06144
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0009360 DNA polymerase III complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06144
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau03440 Homologous recombination 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00230 Purine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau03030 DNA replication 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF06144 DNA polymerase III, delta subunit IPR010372 DNA polymerase III delta, N-terminal 20 191 2.1E-32
Pfam PF14840 Processivity clamp loader gamma complex DNA pol III C-term IPR032780 DNA polymerase III subunit delta, C-terminal 216 339 8.6E-14
CDD cd18138 HLD_clamp_pol_III_delta - - 143 207 9.82671E-27
NCBIfam TIGR01128 JCVI: DNA polymerase III subunit delta IPR005790 DNA polymerase III, delta subunit 16 336 8.0E-111
FunFam G3DSA:1.10.8.60:FF:000085 DNA polymerase III subunit delta - - 145 213 6.2E-37
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 138 1.3E-47
SUPERFAMILY SSF48019 post-AAA+ oligomerization domain-like IPR008921 DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal 213 337 3.57E-32
PANTHER PTHR34388 DNA POLYMERASE III SUBUNIT DELTA - - 1 338 1.2E-98
Gene3D G3DSA:1.20.272.10 - - - 216 341 2.1E-36
FunFam G3DSA:3.40.50.300:FF:001131 DNA polymerase III subunit delta - - 1 136 2.0E-69
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 1 211 1.31E-49
Gene3D G3DSA:1.10.8.60 - - - 145 213 2.4E-27

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.