Pseudomonas aeruginosa UCBPP-PA14, PA14_17180 (lpxD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009245 lipid A biosynthetic process
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 25173672 Reviewed by curator
Molecular Function GO:0016410 N-acyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01853
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009245 lipid A biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01853
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016747 transferase activity, transferring acyl groups other than amino-acyl groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF04613
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Lipid A biosynthesis; third step ECO:0000037
not_recorded
KEGG pau00540 Lipopolysaccharide biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.20.5.170 - - - 313 353 4.4E-20
Pfam PF00132 Bacterial transferase hexapeptide (six repeats) IPR001451 Hexapeptide repeat 149 183 1.5E-6
CDD cd03352 LbH_LpxD IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 112 317 3.02782E-113
Gene3D G3DSA:2.160.10.10 Hexapeptide repeat proteins - - 102 312 1.6E-68
NCBIfam TIGR01853 JCVI: UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 11 332 5.4E-118
PANTHER PTHR43378 UDP-3-O-ACYLGLUCOSAMINE N-ACYLTRANSFERASE IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 7 340 9.6E-77
SUPERFAMILY SSF51161 Trimeric LpxA-like enzymes IPR011004 Trimeric LpxA-like superfamily 35 320 1.75E-80
Hamap MF_00523 UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [lpxD]. IPR007691 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD 12 329 36.407135
Pfam PF04613 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD IPR020573 UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, non-repeat region 25 92 7.9E-22
Coils Coil Coil - - 319 346 -
Gene3D G3DSA:3.40.1390.10 - - - 2 101 1.5E-37

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.