Pseudomonas aeruginosa UCBPP-PA14, PA14_17420 (ispF)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0008685 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02542
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016114 terpenoid biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02542
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00900 Terpenoid backbone biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Isoprenoid biosynthesis; Isopentenyl-PP biosynthesis via DXP pathway; Isopentenyl-PP from 1-deoxy-D-xylulose 5-phosphate: step 4 ECO:0000037
not_recorded
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00107 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase [ispF]. IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1 156 37.064861
FunFam G3DSA:3.30.1330.50:FF:000001 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase - - 1 157 3.1E-81
Gene3D G3DSA:3.30.1330.50 - IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily 1 157 6.4E-76
NCBIfam TIGR00151 JCVI: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 155 5.5E-73
PANTHER PTHR43181 2-C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE SYNTHASE, CHLOROPLASTIC IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1 156 4.1E-70
SUPERFAMILY SSF69765 IpsF-like IPR036571 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase superfamily 1 155 4.32E-67
Pfam PF02542 YgbB family IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1 154 1.8E-67
CDD cd00554 MECDP_synthase IPR003526 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 2 154 4.82101E-93

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.