Pseudomonas aeruginosa UCBPP-PA14, PA14_52240

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0016310	phosphorylation	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:SSF47384	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0016020	membrane	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00672	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0007165	signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00672	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other UCBPP-PA14 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCAP		Two-component System		ECO:0000037 not_recorded
KEGG	pau02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
SMART	SM00387	HKATPase_4	IPR003594	Histidine kinase/HSP90-like ATPase	337	445	2.5E-25
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	340	431	3.3E-14
SUPERFAMILY	SSF47384	Homodimeric domain of signal transducing histidine kinase	IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	217	291	1.96E-11
SUPERFAMILY	SSF158472	HAMP domain-like	-	-	177	229	4.05E-7
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	392	402	1.1E-6
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	374	388	1.1E-6
Gene3D	G3DSA:3.30.450.170	-	IPR038428	Two-component histidine kinase, sensor domain superfamily	26	149	3.8E-35
Gene3D	G3DSA:1.10.287.130	-	-	-	233	291	1.3E-6
Gene3D	G3DSA:3.30.565.10	-	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	320	445	3.0E-28
CDD	cd06225	HAMP	-	-	182	227	7.99015E-9
Coils	Coil	Coil	-	-	266	286	-
SUPERFAMILY	SSF55874	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	IPR036890	Histidine kinase/HSP90-like ATPase superfamily	282	443	1.7E-31
SMART	SM00388	HisKA_10	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	233	292	4.5E-11
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	407	425	1.1E-6
CDD	cd00082	HisKA	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	231	287	3.35933E-8
Pfam	PF00672	HAMP domain	IPR003660	HAMP domain	174	228	1.2E-12
SMART	SM00304	HAMP_11	IPR003660	HAMP domain	177	232	1.7E-10
Gene3D	G3DSA:6.10.340.10	-	-	-	154	232	9.0E-13
Pfam	PF16750	Sensor domain of 2-component histidine kinase	IPR031930	Two-component histidine kinase, sensor domain	39	148	4.2E-35
Pfam	PF00512	His Kinase A (phospho-acceptor) domain	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	234	291	2.3E-9
PANTHER	PTHR45436	SENSOR HISTIDINE KINASE YKOH	-	-	4	445	7.7E-51

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.