Pseudomonas aeruginosa PAO1, PA0668 (tyrZ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006568 tryptophan metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0044267 cellular protein metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006520 cellular amino acid metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0043039 tRNA aminoacylation
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004106 chorismate mutase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006437 tyrosyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00234
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003723 RNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.10.290.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00579
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004831 tyrosine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00234
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00579
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00579
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00579
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Tryptophan metabolism ECO:0000037
not_recorded
PseudoCAP Aminoacyl-tRNA biosynthesis ECO:0000037
not_recorded
KEGG pae00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc TRNA-CHARGING-PWY tRNA charging 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:1.10.240.10:FF:000006 Tyrosine--tRNA ligase - - 219 325 2.9E-45
NCBIfam TIGR00234 JCVI: tyrosine--tRNA ligase IPR002307 Tyrosine-tRNA ligase 2 396 5.3E-119
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 2 218 9.0E-83
PANTHER PTHR11766 TYROSYL-TRNA SYNTHETASE IPR024088 Tyrosine-tRNA ligase, bacterial-type 11 392 1.8E-87
Pfam PF00579 tRNA synthetases class I (W and Y) IPR002305 Aminoacyl-tRNA synthetase, class Ic 31 315 9.6E-81
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 211 223 2.2E-26
SUPERFAMILY SSF55174 Alpha-L RNA-binding motif - - 320 396 9.68E-14
FunFam G3DSA:3.40.50.620:FF:000061 Tyrosine--tRNA ligase - - 2 218 1.6E-124
Hamap MF_02007 Tyrosine--tRNA ligase [tyrS]. IPR024108 Tyrosine-tRNA ligase, bacterial-type, type 2 2 396 48.201878
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 178 200 2.2E-26
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 161 176 2.2E-26
CDD cd00805 TyrRS_core IPR002307 Tyrosine-tRNA ligase 34 298 8.29218E-115
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 4 310 2.43E-99
Gene3D G3DSA:3.10.290.10 - IPR036986 RNA-binding S4 domain superfamily 323 387 6.7E-11
Gene3D G3DSA:1.10.240.10 - - - 219 322 9.8E-37
PRINTS PR01040 Tyrosyl-tRNA synthetase signature IPR002307 Tyrosine-tRNA ligase 46 68 2.2E-26

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.