Pseudomonas aeruginosa PAO1, PA0847

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse View in GBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0052621 diguanylate cyclase activity
IDA
Inferred from Direct Assay
ECO:0000005
enzyme assay evidence
16477007 Reviewed by curator
Molecular Function GO:0009975 cyclase activity

Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00989
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016021 integral component of membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd06225
ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd06225
ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Motility & Attachment Other PAO1 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF05228 CHASE4 domain IPR007892 CHASE4 137 299 4.7E-28
SMART SM00267 IPR000160 GGDEF domain 560 731 1.9E-63
Pfam PF00672 HAMP domain IPR003660 HAMP domain 395 442 8.9E-8
ProSiteProfiles PS50887 GGDEF domain profile. IPR000160 GGDEF domain 601 733 33.239
ProSiteProfiles PS50885 HAMP domain profile. IPR003660 HAMP domain 394 446 9.723
Gene3D G3DSA:3.30.70.270 570 733 8.5E-57
TIGRFAM TIGR00229 sensory_box: PAS domain S-box protein IPR000014 PAS domain 443 567 3.9E-23
Gene3D G3DSA:3.30.450.20 454 569 2.8E-23
Coils Coil 427 447 -
Pfam PF00990 Diguanylate cyclase, GGDEF domain IPR000160 GGDEF domain 571 725 3.1E-45
SMART SM00091 IPR000014 PAS domain 446 512 6.3E-15
TIGRFAM TIGR00254 GGDEF: diguanylate cyclase (GGDEF) domain IPR000160 GGDEF domain 569 727 3.6E-42
Pfam PF00989 PAS fold IPR013767 PAS fold 447 557 1.1E-15
SUPERFAMILY SSF55073 IPR029787 Nucleotide cyclase 576 731 1.49E-46
CDD cd00130 PAS IPR000014 PAS domain 455 557 1.53462E-17
SUPERFAMILY SSF158472 395 443 7.98E-5
SMART SM00304 IPR003660 HAMP domain 394 446 3.2E-7
ProSiteProfiles PS50112 PAS repeat profile. IPR000014 PAS domain 444 514 18.795
Gene3D G3DSA:1.10.287.130 395 453 3.0E-6
CDD cd01949 GGDEF IPR000160 GGDEF domain 572 729 7.03489E-63
ProSiteProfiles PS50113 PAC domain profile. IPR000700 PAS-associated, C-terminal 517 569 12.342
SUPERFAMILY SSF55785 IPR035965 PAS domain superfamily 433 558 5.32E-28
SMART SM00086 IPR001610 PAC motif 518 560 8.1E-5
CDD cd06225 HAMP IPR003660 HAMP domain 396 443 7.78834E-6

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.