Pseudomonas aeruginosa PAO1, PA1246 (aprD)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0046903 secretion
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 1427098 Reviewed by curator
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00382
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0055085 transmembrane transport
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00664
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0030253 protein secretion by the type I secretion system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01842
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01842
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01842
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0140359 ABC-type transmembrane transporter activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00664
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0030256 type I protein secretion system complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01842
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Protein secretion/export apparatus Other PAO1 genes in this class
Secreted Factors (toxins, enzymes, alginate) Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Apr type I secretion system ECO:0000037
not_recorded
KEGG pae02010 ABC transporters 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00005 ABC transporter IPR003439 ABC transporter-like, ATP-binding domain 349 496 1.9E-28
PANTHER PTHR24221 ATP-BINDING CASSETTE SUB-FAMILY B IPR039421 Type 1 protein exporter 27 556 6.7E-73
SUPERFAMILY SSF90123 ABC transporter transmembrane region IPR036640 ABC transporter type 1, transmembrane domain superfamily 19 320 5.76E-45
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 334 571 2.2E-70
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 322 556 1.84E-62
FunFam G3DSA:3.40.50.300:FF:001444 ABC transporter ATP-binding protein - - 327 559 8.7E-101
CDD cd18586 ABC_6TM_PrtD_like IPR047957 Alkaline protease secretion ATP-binding protein AprD-like, 6TM domain 20 309 7.97908E-115
FunFam G3DSA:1.20.1560.10:FF:000109 Alkaline protease secretion ATP-binding protein aprD - - 12 316 0.0
Gene3D G3DSA:1.20.1560.10 ABC transporter type 1, transmembrane domain IPR036640 ABC transporter type 1, transmembrane domain superfamily 14 315 2.9E-31
SMART SM00382 AAA_5 IPR003593 AAA+ ATPase domain 358 544 2.6E-14
Pfam PF00664 ABC transporter transmembrane region IPR011527 ABC transporter type 1, transmembrane domain 34 282 2.2E-12
NCBIfam TIGR01842 JCVI: type I secretion system permease/ATPase IPR010128 ATPase, type I secretion system, PrtD-like 16 558 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.