Pseudomonas aeruginosa PAO1, PA3570 (mmsA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006520 cellular amino acid metabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0015976 carbon utilization
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0044248 cellular catabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0006552 leucine catabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0019541 propionate metabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0004040 amidase activity
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0006550 isoleucine catabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0016491 oxidoreductase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00171
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004491 methylmalonate-semialdehyde dehydrogenase (acylating) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd07085
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016620 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.309.10
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other PAO1 genes in this class
Amino acid biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Propanoate metabolism ECO:0000037
not_recorded
KEGG pae00410 beta-Alanine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00562 Inositol phosphate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae00640 Propanoate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc VALDEG-PWY L-valine degradation I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00280 Valine, leucine and isoleucine degradation 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Valine, leucine and isoleucine degradation ECO:0000037
not_recorded
KEGG pae01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.309.10 Aldehyde Dehydrogenase; Chain A, domain 2 IPR016163 Aldehyde dehydrogenase, C-terminal 250 450 0.0
NCBIfam TIGR01722 JCVI: CoA-acylating methylmalonate-semialdehyde dehydrogenase IPR010061 Methylmalonate-semialdehyde dehydrogenase 5 481 0.0
Pfam PF00171 Aldehyde dehydrogenase family IPR015590 Aldehyde dehydrogenase domain 18 477 0.0
Coils Coil Coil - - 41 61 -
PANTHER PTHR43866 MALONATE-SEMIALDEHYDE DEHYDROGENASE IPR010061 Methylmalonate-semialdehyde dehydrogenase 4 494 0.0
Gene3D G3DSA:3.40.605.10 Aldehyde Dehydrogenase; Chain A, domain 1 IPR016162 Aldehyde dehydrogenase, N-terminal 25 458 0.0
FunFam G3DSA:3.40.309.10:FF:000002 Methylmalonate-semialdehyde dehydrogenase (Acylating) - - 250 450 2.3E-89
CDD cd07085 ALDH_F6_MMSDH IPR010061 Methylmalonate-semialdehyde dehydrogenase 5 481 0.0
FunFam G3DSA:3.40.605.10:FF:000003 Methylmalonate-semialdehyde dehydrogenase [acylating] - - 9 256 1.9E-108
SUPERFAMILY SSF53720 ALDH-like IPR016161 Aldehyde/histidinol dehydrogenase 3 483 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.