Pseudomonas aeruginosa PAO1, PA3620 (mutS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006259 DNA metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006281 DNA repair
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 1651234 Reviewed by curator
Molecular Function GO:0030983 mismatched DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05188
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05188
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006298 mismatch repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF05188
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0140664 ATP-dependent DNA damage sensor activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR11361
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.10.1420.10 - - - 386 502 3.7E-111
SUPERFAMILY SSF53150 DNA repair protein MutS, domain II IPR036678 MutS, connector domain superfamily 114 266 9.16E-44
NCBIfam TIGR01070 JCVI: DNA mismatch repair protein MutS IPR005748 DNA mismatch repair protein MutS 7 852 0.0
Pfam PF05188 MutS domain II IPR007860 DNA mismatch repair protein MutS, connector domain 128 253 4.6E-31
Gene3D G3DSA:6.10.140.430 - - - 825 853 8.6E-11
MobiDBLite mobidb-lite consensus disorder prediction - - 796 816 -
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 567 823 2.2E-101
Pfam PF05190 MutS family domain IV IPR007861 DNA mismatch repair protein MutS, clamp 427 517 5.3E-28
CDD cd03284 ABC_MutS1 - - 578 791 6.26228E-128
Gene3D G3DSA:3.30.420.110 MutS, connector domain IPR036678 MutS, connector domain superfamily 127 260 4.0E-43
FunFam G3DSA:3.40.1170.10:FF:000001 DNA mismatch repair protein MutS - - 1 121 4.5E-58
SUPERFAMILY SSF55271 DNA repair protein MutS, domain I IPR016151 DNA mismatch repair protein MutS, N-terminal 3 115 6.28E-43
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 568 795 9.11E-59
Gene3D G3DSA:3.40.1170.10 DNA repair protein MutS, domain I IPR016151 DNA mismatch repair protein MutS, N-terminal 1 121 5.8E-47
SMART SM00533 DNAend IPR007696 DNA mismatch repair protein MutS, core 283 590 6.2E-109
FunFam G3DSA:3.30.420.110:FF:000001 DNA mismatch repair protein MutS - - 127 262 4.4E-62
SUPERFAMILY SSF48334 DNA repair protein MutS, domain III IPR036187 DNA mismatch repair protein MutS, core domain superfamily 267 564 7.06E-85
PIRSF PIRSF037677 Msh6 IPR017261 DNA mismatch repair protein MutS/MSH 200 833 7.1E-124
Pfam PF05192 MutS domain III IPR007696 DNA mismatch repair protein MutS, core 270 558 1.9E-38
Hamap MF_00096 DNA mismatch repair protein MutS [mutS]. IPR005748 DNA mismatch repair protein MutS 7 847 25.302929
PIRSF PIRSF037677 Msh6 IPR017261 DNA mismatch repair protein MutS/MSH 2 180 2.7E-27
PANTHER PTHR11361 DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER IPR045076 DNA mismatch repair MutS family 11 800 0.0
SMART SM00534 mutATP5 IPR000432 DNA mismatch repair protein MutS, C-terminal 606 792 1.4E-121
Pfam PF00488 MutS domain V IPR000432 DNA mismatch repair protein MutS, C-terminal 609 795 7.8E-86
Coils Coil Coil - - 513 533 -
Pfam PF01624 MutS domain I IPR007695 DNA mismatch repair protein MutS-like, N-terminal 8 119 1.9E-41
FunFam G3DSA:1.10.1420.10:FF:000002 DNA mismatch repair protein MutS - - 386 502 3.7E-48
Gene3D G3DSA:1.10.1420.10 - - - 265 559 3.7E-111
MobiDBLite mobidb-lite consensus disorder prediction - - 799 815 -
FunFam G3DSA:3.40.50.300:FF:000283 DNA mismatch repair protein MutS - - 566 820 8.7E-129

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.