Pseudomonas aeruginosa PAO1, PA3636 (kdsA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0015976 carbon utilization
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 10220877 Reviewed by curator
Biological Process GO:0009103 lipopolysaccharide biosynthetic process
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 21042030 Reviewed by curator
Biological Process GO:0009103 lipopolysaccharide biosynthetic process
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 10220877 Reviewed by curator
Cellular Component GO:0009276 Gram-negative-bacterium-type cell wall
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 10220877 Reviewed by curator
Biological Process GO:0036104 Kdo2-lipid A biosynthetic process
IDA
Inferred from Direct Assay 		ECO:0000314
direct assay evidence used in manual assertion		 10220877 Reviewed by curator
Biological Process GO:0044248 cellular catabolic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0008676 3-deoxy-8-phosphooctulonate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01362
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009058 biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00793
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01362
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class
Carbon compound catabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Lipopolysaccharide biosynthesis ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc KDO-PEP-LIPASYN-PWY KDO<SUB>2</SUB>-lipid A and peptidoglycan biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00540 Lipopolysaccharide biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Fructose and mannose metabolism ECO:0000037
not_recorded
PseudoCyc PWY-1269 CMP-3-deoxy-D-manno-octulosonate biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCyc KDO-NAGLIPASYN-PWY superpathway of (Kdo)<SUB>2</SUB>-lipid A biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.20.20.70 Aldolase class I IPR013785 Aldolase-type TIM barrel 1 281 8.8E-114
SUPERFAMILY SSF51569 Aldolase - - 3 277 1.01E-101
FunFam G3DSA:3.20.20.70:FF:000058 2-dehydro-3-deoxyphosphooctonate aldolase - - 1 281 0.0
PANTHER PTHR21057 PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE IPR006269 3-deoxy-8-phosphooctulonate synthase 7 278 1.4E-109
NCBIfam TIGR01362 JCVI: 3-deoxy-8-phosphooctulonate synthase IPR006269 3-deoxy-8-phosphooctulonate synthase 18 273 4.7E-114
Pfam PF00793 DAHP synthetase I family IPR006218 DAHP synthetase I/KDSA 9 273 2.4E-80
Hamap MF_00056 2-dehydro-3-deoxyphosphooctonate aldolase [kdsA]. IPR006269 3-deoxy-8-phosphooctulonate synthase 13 275 48.256344

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.