Pseudomonas aeruginosa PAO1, PA3702 (wspR)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0009975 cyclase activity

Molecular Function GO:0052621 diguanylate cyclase activity
IDA
Inferred from Direct Assay 		ECO:0000005
enzyme assay evidence		 16477007 Reviewed by curator
Molecular Function GO:0052621 diguanylate cyclase activity
IMP
Inferred from Mutant Phenotype 		ECO:0000015
mutant phenotype evidence		 12426335 Reviewed by curator
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00072
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class
Chemotaxis Other PAO1 genes in this class
Motility & Attachment Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Chemotaxis ECO:0000037
not_recorded
PseudoCAP Two-component System ECO:0000037
not_recorded
KEGG pae02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Chemosensory ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 19 133 3.6E-23
NCBIfam TIGR00254 JCVI: diguanylate cyclase (GGDEF) domain IPR000160 GGDEF domain 167 335 1.3E-51
FunFam G3DSA:3.30.70.270:FF:000001 Diguanylate cyclase domain protein - - 166 338 3.4E-55
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 19 151 1.01E-29
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 21 133 3.8E-19
Gene3D G3DSA:3.30.70.270 - IPR043128 Reverse transcriptase/Diguanylate cyclase domain 156 339 2.8E-63
PANTHER PTHR45138 REGULATORY COMPONENTS OF SENSORY TRANSDUCTION SYSTEM - - 59 334 1.0E-74
Gene3D G3DSA:3.40.50.2300 - - - 1 155 1.6E-34
Pfam PF00990 Diguanylate cyclase, GGDEF domain IPR000160 GGDEF domain 172 333 6.9E-50
SMART SM00267 duf1_3 IPR000160 GGDEF domain 160 337 1.5E-60
SUPERFAMILY SSF55073 Nucleotide cyclase IPR029787 Nucleotide cyclase 176 336 4.39E-49
CDD cd17575 REC_WspR-like - - 19 146 9.17425E-88
CDD cd01949 GGDEF IPR000160 GGDEF domain 174 334 3.79697E-68

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.