Pseudomonas aeruginosa PAO1, PA3725 (recJ)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004518 nuclease activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 2649886 Reviewed by curator
Biological Process GO:0006259 DNA metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00644
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006310 DNA recombination
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00644
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008409 5'-3' exonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00644
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02272
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae03430 Mismatch repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae03440 Homologous recombination 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.90.1640.30 - - - 46 322 3.1E-85
Gene3D G3DSA:3.10.310.30 - - - 323 451 2.1E-35
FunFam G3DSA:3.90.1640.30:FF:000001 Single-stranded-DNA-specific exonuclease RecJ - - 46 322 8.7E-127
NCBIfam TIGR00644 JCVI: single-stranded-DNA-specific exonuclease RecJ IPR004610 Bacterial RecJ exonuclease 20 566 0.0
SUPERFAMILY SSF64182 DHH phosphoesterases IPR038763 DHH phosphoesterase superfamily 44 459 1.02E-118
PANTHER PTHR30255 SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE RECJ - - 17 569 0.0
Pfam PF01368 DHH family IPR001667 DDH domain 69 228 1.2E-19
Pfam PF02272 DHHA1 domain IPR003156 DHHA1 domain 318 446 3.4E-29
Pfam PF17768 RecJ OB domain IPR041122 RecJ, OB domain 463 566 5.9E-20

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.