Pseudomonas aeruginosa PAO1, PA3735 (thrC)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0006544	glycine metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Molecular Function	GO:0004424	imidazoleglycerol-phosphate dehydratase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000044 sequence similarity evidence
Biological Process	GO:0051188	obsolete cofactor biosynthetic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0006520	cellular amino acid metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0042816	vitamin B6 metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0006566	threonine metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence
Biological Process	GO:0006563	L-serine metabolic process	IDA Inferred from Direct Assay	ECO:0000002 direct assay evidence

Functional Classifications Manually Assigned by PseudoCAP

Amino acid biosynthesis and metabolism Other PAO1 genes in this class Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
PseudoCyc	THRESYN-PWY	superpathway of L-threonine biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
PseudoCyc	HOMOSER-THRESYN-PWY	L-threonine biosynthesis	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae00260	Glycine, serine and threonine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae00750	Vitamin B6 metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCyc	P4-PWY	superpathway of L-lysine, L-threonine and L-methionine biosynthesis I	19.5	ECO:0000250 sequence similarity evidence used in manual assertion	12867747
KEGG	pae01230	Biosynthesis of amino acids	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Glycine, serine and threonine metabolism		ECO:0000037 not_recorded
KEGG	pae01110	Biosynthesis of secondary metabolites	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01120	Microbial metabolism in diverse environments	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pae01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Vitamin B6 metabolism		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF14821	Threonine synthase N terminus	IPR029144	Threonine synthase, N-terminal	2	80	2.9E-28
Gene3D	G3DSA:3.40.50.1100	-	IPR036052	Tryptophan synthase beta chain-like, PALP domain superfamily	108	455	0.0
FunFam	G3DSA:3.90.1380.10:FF:000002	Threonine synthase	-	-	1	86	3.3E-40
Pfam	PF00291	Pyridoxal-phosphate dependent enzyme	IPR001926	Tryptophan synthase beta chain-like, PALP domain	92	398	1.0E-24
SUPERFAMILY	SSF53686	Tryptophan synthase beta subunit-like PLP-dependent enzymes	IPR036052	Tryptophan synthase beta chain-like, PALP domain superfamily	1	461	0.0
Gene3D	G3DSA:3.90.1380.10	-	IPR037158	Threonine synthase, N-terminal domain superfamily	1	86	1.3E-30
PANTHER	PTHR42690	THREONINE SYNTHASE FAMILY MEMBER	-	-	1	465	0.0
Gene3D	G3DSA:3.40.50.1100	-	IPR036052	Tryptophan synthase beta chain-like, PALP domain superfamily	90	431	0.0
FunFam	G3DSA:3.40.50.1100:FF:000052	Threonine synthase	-	-	215	431	5.7E-94
CDD	cd01560	Thr-synth_2	-	-	2	458	0.0
NCBIfam	TIGR00260	JCVI: threonine synthase	IPR004450	Threonine synthase-like	67	423	5.4E-80

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.