Pseudomonas aeruginosa PAO1, PA4053 (ribE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0051188 obsolete cofactor biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Molecular Function GO:0004746 riboflavin synthase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 8144477 Reviewed by curator
Molecular Function GO:0000906 6,7-dimethyl-8-ribityllumazine synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd09209
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0009349 riboflavin synthase complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF52121
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009231 riboflavin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd09209
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc RIBOSYN2-PWY flavin biosynthesis I (bacteria and plants) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00740 Riboflavin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Riboflavin metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00178 6,7-dimethyl-8-ribityllumazine synthase [ribH]. IPR034964 Lumazine synthase 10 155 30.962444
NCBIfam TIGR00114 JCVI: 6,7-dimethyl-8-ribityllumazine synthase IPR034964 Lumazine synthase 16 151 2.9E-53
PANTHER PTHR21058 6,7-DIMETHYL-8-RIBITYLLUMAZINE SYNTHASE DMRL SYNTHASE LUMAZINE SYNTHASE IPR034964 Lumazine synthase 15 157 1.5E-53
CDD cd09209 Lumazine_synthase-I IPR034964 Lumazine synthase 17 149 5.14788E-76
SUPERFAMILY SSF52121 Lumazine synthase IPR036467 Lumazine/riboflavin synthase superfamily 5 155 7.2E-61
Gene3D G3DSA:3.40.50.960 Lumazine/riboflavin synthase IPR036467 Lumazine/riboflavin synthase superfamily 3 157 1.0E-60
Pfam PF00885 6,7-dimethyl-8-ribityllumazine synthase IPR002180 Lumazine/riboflavin synthase 16 152 3.2E-56
FunFam G3DSA:3.40.50.960:FF:000001 6,7-dimethyl-8-ribityllumazine synthase - - 3 157 1.1E-73

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.