Pseudomonas aeruginosa PAO1, PA4054 (ribB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004746 riboflavin synthase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 9515916 Reviewed by curator
Biological Process GO:0033215 reductive iron assimilation
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 9515916 Reviewed by curator
Biological Process GO:0051188 obsolete cofactor biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0009231 riboflavin biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00180
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008686 3,4-dihydroxy-2-butanone-4-phosphate synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00180
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc RIBOSYN2-PWY flavin biosynthesis I (bacteria and plants) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00740 Riboflavin metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Riboflavin metabolism ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR21327 GTP CYCLOHYDROLASE II-RELATED - - 2 363 1.2E-95
NCBIfam TIGR00506 JCVI: 3,4-dihydroxy-2-butanone-4-phosphate synthase IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB 3 199 1.5E-74
PIRSF PIRSF001259 RibA - - 1 365 1.5E-116
SUPERFAMILY SSF142695 RibA-like IPR036144 GTP cyclohydrolase II superfamily 204 363 5.1E-40
Gene3D G3DSA:3.40.50.10990 GTP cyclohydrolase II IPR036144 GTP cyclohydrolase II superfamily 206 365 6.9E-27
Gene3D G3DSA:3.90.870.10 DHBP synthase - - 1 205 7.7E-90
Hamap MF_00180 3,4-dihydroxy-2-butanone 4-phosphate synthase [ribB]. IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB 1 203 38.815067
FunFam G3DSA:3.90.870.10:FF:000001 Riboflavin biosynthesis protein RibBA - - 1 205 1.0E-97
Pfam PF00925 GTP cyclohydrolase II IPR032677 GTP cyclohydrolase II 208 363 7.7E-31
SUPERFAMILY SSF55821 YrdC/RibB IPR017945 DHBP synthase RibB-like alpha/beta domain superfamily 2 202 5.72E-87
Pfam PF00926 3,4-dihydroxy-2-butanone 4-phosphate synthase IPR000422 3,4-dihydroxy-2-butanone 4-phosphate synthase, RibB 8 198 1.2E-83

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.