Pseudomonas aeruginosa PAO1, PA4217 (phzS)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0002047 | phenazine biosynthetic process | Inferred from Direct Assay | ECO:0000002 direct assay evidence |
||
| Molecular Function | GO:0004497 | monooxygenase activity | Inferred from Direct Assay | ECO:0000314 direct assay evidence used in manual assertion |
17012792 | Reviewed by curator |
| Molecular Function | GO:0003824 | catalytic activity | Inferred from Direct Assay | ECO:0000002 direct assay evidence |
||
| Molecular Function | GO:0071949 | FAD binding |
Inferred from Sequence Model
Term mapped from: InterPro:PF01494
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| PseudoCAP | Phenazine biosynthesis |
ECO:0000037
not_recorded |
|||
| PseudoCyc | PWYB-5652 | Phenazine biosynthesis | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | PWY-6666 | pyocyanin biosynthesis | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Coils | Coil | Coil | - | - | 333 | 353 | - |
| SUPERFAMILY | SSF51905 | FAD/NAD(P)-binding domain | IPR036188 | FAD/NAD(P)-binding domain superfamily | 5 | 366 | 8.42E-66 |
| PRINTS | PR00420 | Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature | - | - | 302 | 317 | 3.5E-21 |
| Pfam | PF01494 | FAD binding domain | IPR002938 | FAD-binding domain | 299 | 362 | 1.9E-9 |
| SUPERFAMILY | SSF54373 | FAD-linked reductases, C-terminal domain | - | - | 185 | 293 | 2.43E-31 |
| MobiDBLite | mobidb-lite | consensus disorder prediction | - | - | 368 | 402 | - |
| PANTHER | PTHR13789 | MONOOXYGENASE | - | - | 3 | 384 | 9.0E-76 |
| Gene3D | G3DSA:3.30.9.30 | - | - | - | 40 | 296 | 0.0 |
| Pfam | PF01494 | FAD binding domain | IPR002938 | FAD-binding domain | 6 | 178 | 4.7E-13 |
| Gene3D | G3DSA:3.50.50.60 | - | IPR036188 | FAD/NAD(P)-binding domain superfamily | 7 | 359 | 0.0 |
| PRINTS | PR00420 | Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature | - | - | 6 | 28 | 3.5E-21 |
| PRINTS | PR00420 | Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature | - | - | 157 | 172 | 3.5E-21 |
| PRINTS | PR00420 | Aromatic-ring hydroxylase (flavoprotein monooxygenase) signature | - | - | 317 | 333 | 3.5E-21 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.