Pseudomonas aeruginosa PAO1, PA4226 (pchE)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006810 transport
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Biological Process GO:0042864 pyochelin biosynthetic process
IDA
Inferred from Direct Assay 		ECO:0000002
direct assay evidence
Molecular Function GO:0031177 phosphopantetheine binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00823
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008757 S-adenosylmethionine-dependent methyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF53335
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00668
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Secreted Factors (toxins, enzymes, alginate) Other PAO1 genes in this class
Transport of small molecules Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Pyochelin synthesis ECO:0000037
not_recorded
KEGG pae01053 Biosynthesis of siderophore group nonribosomal peptides 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-6408 pyochelin biosynthesis 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF00550 Phosphopantetheine attachment site IPR009081 Phosphopantetheine binding ACP domain 1358 1421 5.8E-15
SUPERFAMILY SSF52777 CoA-dependent acyltransferases - - 100 296 9.23E-21
CDD cd12114 A_NRPS_TlmIV_like - - 568 1042 0.0
PANTHER PTHR45527 NONRIBOSOMAL PEPTIDE SYNTHETASE - - 332 1432 0.0
Gene3D G3DSA:3.40.50.150 Vaccinia Virus protein VP39 IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily 1142 1244 2.9E-7
SUPERFAMILY SSF52777 CoA-dependent acyltransferases - - 285 526 1.22E-40
SMART SM00823 Phosphopantetheine attachment site IPR020806 Polyketide synthase, phosphopantetheine-binding domain 1356 1425 4.2E-11
FunFam G3DSA:1.10.1200.10:FF:000021 Isochorismatase - - 8 86 3.2E-28
Pfam PF00668 Condensation domain IPR001242 Condensation domain 136 442 3.0E-29
Gene3D G3DSA:3.30.559.30 Nonribosomal peptide synthetase, condensation domain - - 282 525 1.3E-49
Gene3D G3DSA:3.30.559.10 - IPR023213 Chloramphenicol acetyltransferase-like domain superfamily 98 278 1.4E-28
Gene3D G3DSA:1.10.1200.10 - IPR036736 ACP-like superfamily 5 84 3.0E-16
SUPERFAMILY SSF47336 ACP-like IPR036736 ACP-like superfamily 6 117 9.95E-10
SUPERFAMILY SSF47336 ACP-like IPR036736 ACP-like superfamily 1349 1421 7.07E-17
FunFam G3DSA:1.10.1200.10:FF:000016 Non-ribosomal peptide synthase - - 1344 1427 8.0E-22
SUPERFAMILY SSF56801 Acetyl-CoA synthetase-like - - 543 1333 2.17E-118
Pfam PF00501 AMP-binding enzyme IPR000873 AMP-dependent synthetase/ligase domain 563 950 1.2E-84
FunFam G3DSA:3.30.559.30:FF:000006 Yersiniabactin polyketide/non-ribosomal peptide synthetase - - 283 525 2.3E-91
Gene3D G3DSA:3.30.300.30 - IPR045851 AMP-binding enzyme, C-terminal domain superfamily 944 1054 2.0E-9
CDD cd19535 Cyc_NRPS - - 104 523 0.0
Gene3D G3DSA:3.40.50.12780 - IPR042099 ANL, N-terminal domain 553 943 1.8E-107
SUPERFAMILY SSF53335 S-adenosyl-L-methionine-dependent methyltransferases IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily 1109 1268 7.59E-10
Gene3D G3DSA:1.10.1200.10 - IPR036736 ACP-like superfamily 1342 1429 3.5E-22
FunFam G3DSA:3.30.559.10:FF:000023 Non-ribosomal peptide synthetase - - 99 276 1.4E-64
Pfam PF00550 Phosphopantetheine attachment site IPR009081 Phosphopantetheine binding ACP domain 13 80 1.7E-7
FunFam G3DSA:3.40.50.12780:FF:000012 Non-ribosomal peptide synthetase - - 554 943 8.0E-125
NCBIfam TIGR01733 JCVI: amino acid adenylation domain IPR010071 Amino acid adenylation domain 583 973 7.8E-113
Gene3D G3DSA:3.30.300.30 - IPR045851 AMP-binding enzyme, C-terminal domain superfamily 1252 1341 6.3E-11

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.