Pseudomonas aeruginosa PAO1, PA4234 (uvrA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006259 DNA metabolic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0006289 nucleotide-excision repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0009380 excinuclease repair complex
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016887 ATPase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1490.20
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_00205
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae03420 Nucleotide excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF17755 UvrA DNA-binding domain IPR041552 UvrA DNA-binding domain 291 399 7.0E-32
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 612 910 1.22E-52
FunFam G3DSA:1.20.1580.10:FF:000002 UvrABC system protein A - - 693 830 1.5E-81
FunFam G3DSA:3.30.190.20:FF:000003 UvrABC system protein A - - 135 244 1.1E-49
PANTHER PTHR43152 UVRABC SYSTEM PROTEIN A - - 2 942 0.0
Gene3D G3DSA:3.30.1490.20 - IPR013815 ATP-grasp fold, subdomain 1 209 282 0.0
FunFam G3DSA:1.10.8.280:FF:000001 UvrABC system protein A - - 288 404 1.1E-51
SUPERFAMILY SSF52540 P-loop containing nucleoside triphosphate hydrolases IPR027417 P-loop containing nucleoside triphosphate hydrolase 6 569 3.41E-46
Pfam PF17760 UvrA interaction domain IPR041102 UvrA, interaction domain 130 237 8.9E-41
CDD cd03270 ABC_UvrA_I - - 4 116 2.89597E-75
Gene3D G3DSA:1.10.8.280 - - - 319 437 0.0
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 6 580 0.0
Gene3D G3DSA:1.20.1580.10 ABC transporter ATPase like domain - - 693 830 0.0
NCBIfam TIGR00630 JCVI: excinuclease ABC subunit UvrA IPR004602 UvrABC system subunit A 3 925 0.0
Gene3D G3DSA:3.40.50.300 - IPR027417 P-loop containing nucleoside triphosphate hydrolase 609 937 0.0
CDD cd03271 ABC_UvrA_II - - 617 921 0.0
Gene3D G3DSA:1.20.1580.10 ABC transporter ATPase like domain - - 92 518 0.0
Hamap MF_00205 UvrABC system protein A [uvrA]. IPR004602 UvrABC system subunit A 1 940 22.88081

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.