Pseudomonas aeruginosa PAO1, PA4700 (mrcB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 6389538 Reviewed by curator
Molecular Function GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 6389538 Reviewed by curator
Molecular Function GO:0016757 transferase activity, transferring glycosyl groups
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: CAZy:GT51
 ECO:0000250
sequence similarity evidence used in manual assertion		 18838391 Reviewed by curator
Molecular Function GO:0008955 peptidoglycan glycosyltransferase activity
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000250
sequence similarity evidence used in manual assertion		 6389538 Reviewed by curator
Molecular Function GO:0008955 peptidoglycan glycosyltransferase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF002799
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0046677 response to antibiotic
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF002799
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008233 peptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF002799
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0009274 peptidoglycan-based cell wall
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF002799
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF002799
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008658 penicillin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00905
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCAP Peptideglycan biosynthesis ECO:0000037
not_recorded
KEGG pae00550 Peptidoglycan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.20.5.100 - - - 18 54 3.9E-6
PANTHER PTHR32282 BINDING PROTEIN TRANSPEPTIDASE, PUTATIVE-RELATED - - 4 763 0.0
Gene3D G3DSA:1.10.3810.10 - IPR036950 Penicillin binding protein transglycosylase domain 158 361 0.0
SUPERFAMILY SSF56601 beta-lactamase/transpeptidase-like IPR012338 Beta-lactamase/transpeptidase-like 319 756 4.13E-119
NCBIfam TIGR02071 JCVI: penicillin-binding protein 1B IPR011813 Penicillin-binding protein 1B 26 752 0.0
FunFam G3DSA:1.10.3810.10:FF:000002 Penicillin-binding protein 1B - - 158 361 1.3E-81
SUPERFAMILY SSF53955 Lysozyme-like IPR023346 Lysozyme-like domain superfamily 163 360 6.75E-66
FunFam G3DSA:3.40.710.10:FF:000006 Penicillin-binding protein 1B - - 355 725 0.0
PIRSF PIRSF002799 PBP1b IPR011813 Penicillin-binding protein 1B 1 774 0.0
Pfam PF00912 Transglycosylase IPR001264 Glycosyl transferase, family 51 166 336 1.4E-56
Gene3D G3DSA:3.40.710.10 - IPR012338 Beta-lactamase/transpeptidase-like 61 725 0.0
Pfam PF14814 Bifunctional transglycosylase second domain IPR028166 Bifunctional transglycosylase second domain 71 154 8.5E-25
Gene3D G3DSA:3.30.2060.10 - - - 69 157 0.0
Pfam PF00905 Penicillin binding protein transpeptidase domain IPR001460 Penicillin-binding protein, transpeptidase 431 659 5.5E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.