Pseudomonas aeruginosa PAO1, PA4748 (tpiA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0004807 | triose-phosphate isomerase activity | Inferred from Sequence or Structural Similarity | ECO:0000250 sequence similarity evidence used in manual assertion |
6214548 | Reviewed by curator |
| Biological Process | GO:0006094 | gluconeogenesis | Inferred from Sequence or Structural Similarity | ECO:0000250 sequence similarity evidence used in manual assertion |
11947134 | Reviewed by curator |
| Molecular Function | GO:0004807 | triose-phosphate isomerase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00419
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0006096 | glycolytic process |
Inferred from Sequence Model
Term mapped from: InterPro:MF_00147_B
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | pae00010 | Glycolysis / Gluconeogenesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCyc | GLYCOLYSIS+CITRIC-ACID-PWY | glycolysis + citric acid pathway | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | PWY-5484 | glycolysis II (from fructose 6-phosphate) | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| KEGG | pae01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCyc | GLUCONEO-PWY | gluconeogenesis I | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | GLYCOLYSIS-TCA-GLYOX-BYPASS | superpathway of glycolysis, pyruvate dehydrogenase, TCA, and glyoxylate bypass | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | ANAGLYCOLYSIS-PWY | glycolysis III (from glucose) | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCAP | Carbon fixation |
ECO:0000037
not_recorded |
|||
| KEGG | pae01230 | Biosynthesis of amino acids | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCyc | AERO-GLYCEROL-FERM-PWY | aerobic glycerol degradation I | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| KEGG | pae00051 | Fructose and mannose metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCyc | GLYCOLYSIS-E-D | superpathway of glycolysis and Entner-Doudoroff | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCAP | Fructose and mannose metabolism |
ECO:0000037
not_recorded |
|||
| KEGG | pae01120 | Microbial metabolism in diverse environments | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae00562 | Inositol phosphate metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCAP | Glycerolipid metabolism |
ECO:0000037
not_recorded |
|||
| PseudoCAP | Glycolysis / Gluconeogenesis |
ECO:0000037
not_recorded |
|||
| KEGG | pae01110 | Biosynthesis of secondary metabolites | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pae01200 | Carbon metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| PseudoCyc | GLYCOLYSIS | glycolysis I (from glucose 6-phosphate) | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| PseudoCyc | P461-PWY | hexitol fermentation to lactate, formate, ethanol and acetate | 19.5 |
ECO:0000250
sequence similarity evidence used in manual assertion |
12867747 |
| KEGG | pae01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| PANTHER | PTHR21139 | TRIOSEPHOSPHATE ISOMERASE | IPR000652 | Triosephosphate isomerase | 2 | 247 | 6.8E-77 |
| Pfam | PF00121 | Triosephosphate isomerase | IPR000652 | Triosephosphate isomerase | 4 | 248 | 2.3E-89 |
| SUPERFAMILY | SSF51351 | Triosephosphate isomerase (TIM) | IPR035990 | Triosephosphate isomerase superfamily | 1 | 248 | 2.36E-86 |
| NCBIfam | TIGR00419 | JCVI: triose-phosphate isomerase | IPR000652 | Triosephosphate isomerase | 5 | 240 | 9.6E-66 |
| CDD | cd00311 | TIM | IPR000652 | Triosephosphate isomerase | 4 | 247 | 1.53894E-119 |
| Gene3D | G3DSA:3.20.20.70 | Aldolase class I | IPR013785 | Aldolase-type TIM barrel | 1 | 250 | 1.1E-92 |
| FunFam | G3DSA:3.20.20.70:FF:000016 | Triosephosphate isomerase | - | - | 1 | 250 | 1.2E-92 |
| Hamap | MF_00147_B | Triosephosphate isomerase [tpiA]. | IPR022896 | Triosephosphate isomerase, bacterial/eukaryotic | 2 | 248 | 57.286263 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.