Pseudomonas aeruginosa PAO1, PA4761 (dnaK)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:0006508	proteolysis	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	3149251	Reviewed by curator
Biological Process	GO:0046777	protein autophosphorylation	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	1835085	Reviewed by curator
Molecular Function	GO:0016887	ATPase activity	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	6314326	Reviewed by curator
Biological Process	GO:0006457	protein folding	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	8898387	Reviewed by curator
Biological Process	GO:0030254	protein secretion by the type III secretion system	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	28758636	Reviewed by curator
Biological Process	GO:0043107	type IV pilus-dependent motility	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	28758636	Reviewed by curator
Biological Process	GO:0051701	interaction with host	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	28758636	Reviewed by curator
Biological Process	GO:0042158	lipoprotein biosynthetic process	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	16109938	Reviewed by curator
Biological Process	GO:0006260	DNA replication	ISS Inferred from Sequence or Structural Similarity	ECO:0000250 sequence similarity evidence used in manual assertion	6086613	Reviewed by curator
Biological Process	GO:0071977	bacterial-type flagellum-dependent swimming motility	IMP Inferred from Mutant Phenotype	ECO:0000315 mutant phenotype evidence used in manual assertion	28758636	Reviewed by curator
Molecular Function	GO:0140662	ATP-dependent protein folding chaperone	ISM Inferred from Sequence Model Term mapped from: InterPro:PF00012	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0051082	unfolded protein binding	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00332	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00332	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006457	protein folding	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_00332	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Chaperones & heat shock proteins Other PAO1 genes in this class DNA replication, recombination, modification and repair Other PAO1 genes in this class Adaptation, Protection Other PAO1 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pae03018	RNA degradation	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Gene3D	G3DSA:1.20.1270.10	-	IPR029048	Heat shock protein 70kD, C-terminal domain superfamily	507	607	6.7E-29
FunFam	G3DSA:1.20.1270.10:FF:000001	Molecular chaperone DnaK	-	-	507	609	2.6E-32
PRINTS	PR00301	70kDa heat shock protein signature	-	-	138	158	8.0E-81
Gene3D	G3DSA:2.60.34.10	Substrate Binding Domain Of DNAk; Chain A, domain 1	IPR029047	Heat shock protein 70kD, peptide-binding domain superfamily	380	506	3.2E-55
FunFam	G3DSA:3.30.30.30:FF:000003	Heat shock protein 9	-	-	67	118	5.6E-18
PRINTS	PR00301	70kDa heat shock protein signature	-	-	54	62	8.0E-81
SUPERFAMILY	SSF53067	Actin-like ATPase domain	IPR043129	ATPase, nucleotide binding domain	187	382	2.07E-69
FunFam	G3DSA:3.90.640.10:FF:000003	Molecular chaperone DnaK	-	-	229	316	1.7E-37
FunFam	G3DSA:3.30.420.40:FF:000004	Molecular chaperone DnaK	-	-	5	192	8.9E-92
Hamap	MF_00332	Chaperone protein DnaK [dnaK].	IPR012725	Chaperone DnaK	1	633	36.887924
PRINTS	PR00301	70kDa heat shock protein signature	-	-	388	407	8.0E-81
PRINTS	PR00301	70kDa heat shock protein signature	-	-	31	43	8.0E-81
PANTHER	PTHR19375	HEAT SHOCK PROTEIN 70KDA	IPR013126	Heat shock protein 70 family	5	566	0.0
Gene3D	G3DSA:3.30.420.40	-	-	-	180	366	0.0
Gene3D	G3DSA:3.90.640.10	Actin; Chain A, domain 4	-	-	229	316	0.0
NCBIfam	TIGR02350	JCVI: molecular chaperone DnaK	IPR012725	Chaperone DnaK	3	603	0.0
PRINTS	PR00301	70kDa heat shock protein signature	-	-	469	485	8.0E-81
Gene3D	G3DSA:3.30.420.40	-	-	-	5	379	0.0
SUPERFAMILY	SSF53067	Actin-like ATPase domain	IPR043129	ATPase, nucleotide binding domain	4	183	8.85E-66
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	622	637	-
PRINTS	PR00301	70kDa heat shock protein signature	-	-	3	16	8.0E-81
Pfam	PF00012	Hsp70 protein	IPR013126	Heat shock protein 70 family	4	603	0.0
PRINTS	PR00301	70kDa heat shock protein signature	-	-	334	350	8.0E-81
MobiDBLite	mobidb-lite	consensus disorder prediction	-	-	603	637	-
Coils	Coil	Coil	-	-	259	279	-
FunFam	G3DSA:2.60.34.10:FF:000014	Chaperone protein DnaK HSP70	-	-	378	562	1.5E-77
PRINTS	PR00301	70kDa heat shock protein signature	-	-	365	385	8.0E-81
PRINTS	PR00301	70kDa heat shock protein signature	-	-	198	208	8.0E-81
SUPERFAMILY	SSF100920	Heat shock protein 70kD (HSP70), peptide-binding domain	IPR029047	Heat shock protein 70kD, peptide-binding domain superfamily	384	539	3.66E-60
SUPERFAMILY	SSF100934	Heat shock protein 70kD (HSP70), C-terminal subdomain	IPR029048	Heat shock protein 70kD, C-terminal domain superfamily	507	603	1.01E-23

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.