Pseudomonas aeruginosa PAO1, PA5124 (ntrB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0000160 phosphorelay signal transduction system
ISS
Inferred from Sequence or Structural Similarity 		ECO:0000044
sequence similarity evidence
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47384
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47384
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pae02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCAP Two-component System ECO:0000037
not_recorded

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR43065 SENSOR HISTIDINE KINASE - - 5 355 4.2E-49
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 235 355 2.7E-26
FunFam G3DSA:3.30.565.10:FF:000008 Nitrogen regulation histidine kinase - - 194 355 1.1E-77
CDD cd00130 PAS IPR000014 PAS domain 14 114 6.65072E-4
CDD cd16918 HATPase_Glnl-NtrB-like - - 240 352 1.77892E-64
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 339 352 1.7E-10
SMART SM00091 pas_2 IPR000014 PAS domain 5 73 9.8E-5
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 195 354 2.7E-37
Gene3D G3DSA:1.10.287.130 - - - 116 192 3.7E-14
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 125 193 5.3E-13
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 316 334 1.7E-10
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 135 188 3.8E-15
Gene3D G3DSA:3.30.450.20 PAS domain - - 3 114 7.8E-21
FunFam G3DSA:1.10.287.130:FF:000005 Nitrogen regulation histidine kinase - - 117 192 1.4E-43
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 236 355 1.4E-14
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 287 301 1.7E-10
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 6 104 1.54E-8
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 198 353 9.56E-34
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 131 196 3.2E-15
Pfam PF00989 PAS fold IPR013767 PAS fold 8 104 5.8E-6
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 135 188 1.37895E-11

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.