Pseudomonas aeruginosa PAO1, PA5321 (dut)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse PseudoCyc / Metabolic Pathways

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005829 cytosol
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P06968
 ECO:0000250
sequence similarity evidence used in manual assertion		 16858726 Reviewed by curator
Molecular Function GO:0004170 dUTP diphosphatase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P06968
 ECO:0000250
sequence similarity evidence used in manual assertion		 346589 Reviewed by curator
Biological Process GO:0046081 dUTP catabolic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: UniProtKB:P06968
 ECO:0000250
sequence similarity evidence used in manual assertion		 346589 Reviewed by curator
Biological Process GO:0006226 dUMP biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00576
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0046081 dUTP catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00576
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000287 magnesium ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00576
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004170 dUTP diphosphatase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00576
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other PAO1 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
PseudoCyc PWY-7187 pyrimidine deoxyribonucleotides de novo biosynthesis II 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
PseudoCAP Pyrimidine metabolism ECO:0000037
not_recorded
KEGG pae01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY0-166 superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis (E. coli) 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747
KEGG pae00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
PseudoCyc PWY-7184 pyrimidine deoxyribonucleotides de novo biosynthesis I 19.5 ECO:0000250
sequence similarity evidence used in manual assertion 		12867747

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd07557 trimeric_dUTPase IPR033704 dUTPase, trimeric 28 121 1.20454E-29
NCBIfam TIGR00576 JCVI: dUTP diphosphatase IPR008181 Deoxyuridine triphosphate nucleotidohydrolase 10 150 5.9E-47
FunFam G3DSA:2.70.40.10:FF:000002 dUTP diphosphatase - - 1 151 7.5E-76
Gene3D G3DSA:2.70.40.10 - IPR036157 dUTPase-like superfamily 1 150 2.6E-54
SUPERFAMILY SSF51283 dUTPase-like IPR036157 dUTPase-like superfamily 2 149 1.57E-52
Pfam PF00692 dUTPase IPR029054 dUTPase-like 17 149 5.6E-40
PANTHER PTHR11241 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE IPR008181 Deoxyuridine triphosphate nucleotidohydrolase 11 149 4.0E-34
Hamap MF_00116 Deoxyuridine 5'-triphosphate nucleotidohydrolase [dut]. IPR008181 Deoxyuridine triphosphate nucleotidohydrolase 6 150 33.191273

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.