Pseudomonas fluorescens F113, PSF113_5525 (cheA5)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004673 protein histidine kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0000160 phosphorelay signal transduction system
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF47226
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006935 chemotaxis
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50341
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM01231
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pfe02020 Two-component system 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pfe02025 Biofilm formation - Pseudomonas aeruginosa 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 14 129 7.2E-12
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 769 862 1.5E-9
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 627 724 9.2E-9
Pfam PF02895 Signal transducing histidine kinase, homodimeric domain IPR004105 Histidine kinase CheA-like, homodimeric domain 1370 1507 1.8E-5
Coils Coil Coil - - 1078 1098 -
SUPERFAMILY SSF50341 CheW-like IPR036061 CheW-like domain superfamily 1693 1826 2.75E-24
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1213 1313 6.9E-16
Pfam PF00072 Response regulator receiver domain IPR001789 Signal transduction response regulator, receiver domain 1856 1967 2.9E-27
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1598 1612 2.1E-10
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 1553 1694 4.8E-22
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 907 1029 1.65E-14
Coils Coil Coil - - 1407 1427 -
Pfam PF01584 CheW-like domain IPR002545 CheW-like domain 1699 1828 5.1E-22
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1510 1691 7.99E-36
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 7 130 1.22E-21
Gene3D G3DSA:3.40.50.2300 - - - 1856 1975 2.8E-41
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 627 760 8.1E-28
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1073 1172 9.3E-14
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1211 1308 7.5E-12
MobiDBLite mobidb-lite consensus disorder prediction - - 1334 1368 -
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1211 1309 2.83506E-15
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 629 715 7.7E-14
FunFam G3DSA:3.30.565.10:FF:000016 Chemotaxis protein CheA, putative - - 1509 1693 4.9E-59
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 1557 1693 1.9E-13
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1069 1167 2.0E-6
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 769 840 1.43273E-7
Gene3D G3DSA:2.30.30.40 SH3 Domains - - 1768 1828 4.2E-20
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 1507 1693 3.9E-51
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 627 714 1.00916E-8
Coils Coil Coil - - 1473 1493 -
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1654 1672 2.1E-10
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1210 1345 1.5E-32
MobiDBLite mobidb-lite consensus disorder prediction - - 1346 1360 -
MobiDBLite mobidb-lite consensus disorder prediction - - 604 623 -
SMART SM00073 hpt_2 IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 765 862 9.3E-4
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 432 557 4.71E-16
SUPERFAMILY SSF52172 CheY-like IPR011006 CheY-like superfamily 1853 1972 1.42E-37
CDD cd17546 REC_hyHK_CKI1_RcsC-like - - 1856 1967 5.72395E-33
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1211 1331 2.09E-30
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 766 888 3.66E-18
SMART SM01231 H_kinase_dim_2 IPR004105 Histidine kinase CheA-like, homodimeric domain 1369 1508 2.0E-11
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 908 1036 8.9E-13
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 627 746 1.7E-26
CDD cd00088 HPT IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 1071 1156 2.42217E-12
Pfam PF01627 Hpt domain IPR008207 Signal transduction histidine kinase, phosphotransfer (Hpt) domain 10 99 8.9E-8
PANTHER PTHR43395 SENSOR HISTIDINE KINASE CHEA - - 628 754 0.0
SMART SM00260 chew_2 IPR002545 CheW-like domain 1686 1830 1.6E-27
SUPERFAMILY SSF47226 Histidine-containing phosphotransfer domain, HPT domain IPR036641 HPT domain superfamily 1071 1192 1.18E-25
Coils Coil Coil - - 67 87 -
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 1069 1203 3.9E-26
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 1678 1691 2.1E-10
SMART SM00448 REC_2 IPR001789 Signal transduction response regulator, receiver domain 1854 1967 8.9E-37
Gene3D G3DSA:1.20.120.160 HPT domain IPR036641 HPT domain superfamily 761 895 8.5E-18

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.