Pseudomonas fluorescens SBW25, PFLU0024 (aroE)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004764	shikimate 3-dehydrogenase (NADP+) activity	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00507	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0019632	shikimate metabolic process	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00507	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0050661	NADP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:TIGR00507	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
UniPathway	UPA00053	chorismate biosynthesis	InterPro 5.8-49.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion	0
KEGG (InterPro)	00400	Phenylalanine, tyrosine and tryptophan biosynthesis	InterPro 5.8-49.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion	0

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
FunFam	G3DSA:3.40.50.720:FF:000104	Shikimate dehydrogenase (NADP(+))	-	-	101	245	2.0E-55
Pfam	PF01488	Shikimate / quinate 5-dehydrogenase	IPR006151	Quinate/shikimate 5-dehydrogenase/glutamyl-tRNA reductase	116	191	1.8E-9
Gene3D	G3DSA:3.40.50.720	-	-	-	101	245	2.1E-89
Gene3D	G3DSA:3.40.50.10860	Leucine Dehydrogenase, chain A, domain 1	-	-	6	255	2.1E-89
FunFam	G3DSA:3.40.50.10860:FF:000006	Shikimate dehydrogenase (NADP(+))	-	-	5	120	4.9E-40
SUPERFAMILY	SSF51735	NAD(P)-binding Rossmann-fold domains	IPR036291	NAD(P)-binding domain superfamily	101	270	3.66E-39
Pfam	PF18317	Shikimate 5'-dehydrogenase C-terminal domain	IPR041121	SDH, C-terminal	238	267	3.9E-11
CDD	cd01065	NAD_bind_Shikimate_DH	-	-	100	255	3.17208E-43
NCBIfam	TIGR00507	JCVI: shikimate dehydrogenase	IPR011342	Shikimate dehydrogenase	4	271	8.5E-75
Pfam	PF08501	Shikimate dehydrogenase substrate binding domain	IPR013708	Shikimate dehydrogenase substrate binding, N-terminal	6	87	2.3E-22
PANTHER	PTHR21089	SHIKIMATE DEHYDROGENASE	IPR022893	Shikimate dehydrogenase family	2	259	3.2E-60
SUPERFAMILY	SSF53223	Aminoacid dehydrogenase-like, N-terminal domain	IPR046346	Aminoacid dehydrogenase-like, N-terminal domain superfamily	1	100	1.38E-28
Hamap	MF_00222	Shikimate dehydrogenase (NADP(+)) [aroE].	IPR022893	Shikimate dehydrogenase family	1	270	31.094944

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.