Pseudomonas fluorescens SBW25, PFLU5652 (glyA)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0019264 | glycine biosynthetic process from serine |
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0030170 | pyridoxal phosphate binding |
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Biological Process | GO:0035999 | tetrahydrofolate interconversion |
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004372 | glycine hydroxymethyltransferase activity |
Inferred from Sequence Model
Term mapped from: InterPro:cd00378
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG (InterPro) | 00460 | Cyanoamino acid metabolism | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| UniPathway | UPA00288 | glycine biosynthesis | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| KEGG (InterPro) | 00670 | One carbon pool by folate | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| KEGG (InterPro) | 00630 | Glyoxylate and dicarboxylate metabolism | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| UniPathway | UPA00193 | tetrahydrofolate interconversion | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| KEGG (InterPro) | 00260 | Glycine, serine and threonine metabolism | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
| KEGG (InterPro) | 00680 | Methane metabolism | InterPro 5.8-49.0 |
ECO:0000259
match to InterPro signature evidence used in automatic assertion |
0 |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Pfam | PF00464 | Serine hydroxymethyltransferase | IPR039429 | Serine hydroxymethyltransferase-like domain | 10 | 386 | 0.0 |
| PIRSF | PIRSF000412 | SHMT | IPR001085 | Serine hydroxymethyltransferase | 1 | 415 | 0.0 |
| SUPERFAMILY | SSF53383 | PLP-dependent transferases | IPR015424 | Pyridoxal phosphate-dependent transferase | 8 | 416 | 0.0 |
| FunFam | G3DSA:3.90.1150.10:FF:000003 | Serine hydroxymethyltransferase | - | - | 275 | 416 | 2.3E-59 |
| Gene3D | G3DSA:3.90.1150.10 | Aspartate Aminotransferase, domain 1 | IPR015422 | Pyridoxal phosphate-dependent transferase, small domain | 12 | 416 | 0.0 |
| PANTHER | PTHR11680 | SERINE HYDROXYMETHYLTRANSFERASE | IPR001085 | Serine hydroxymethyltransferase | 7 | 388 | 0.0 |
| Hamap | MF_00051 | Serine hydroxymethyltransferase [glyA]. | IPR001085 | Serine hydroxymethyltransferase | 7 | 417 | 52.536156 |
| CDD | cd00378 | SHMT | IPR001085 | Serine hydroxymethyltransferase | 11 | 409 | 0.0 |
| FunFam | G3DSA:3.40.640.10:FF:000001 | Serine hydroxymethyltransferase | - | - | 37 | 280 | 0.0 |
| Gene3D | G3DSA:3.40.640.10 | - | IPR015421 | Pyridoxal phosphate-dependent transferase, major domain | 37 | 280 | 0.0 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.