Pseudomonas fluorescens SBW25, PFLU6054 (purK)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0004638	phosphoribosylaminoimidazole carboxylase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_01928	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005524	ATP binding	ISM Inferred from Sequence Model Term mapped from: InterPro:G3DSA:3.30.1490.20	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0006189	'de novo' IMP biosynthetic process	ISM Inferred from Sequence Model Term mapped from: InterPro:MF_01928	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
UniPathway	UPA00074	IMP biosynthesis via de novo pathway	InterPro 5.8-49.0	ECO:0000259 match to InterPro signature evidence used in automatic assertion	0

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
FunFam	G3DSA:3.30.470.20:FF:000029	N5-carboxyaminoimidazole ribonucleotide synthase	-	-	176	359	1.0E-71
FunFam	G3DSA:3.30.1490.20:FF:000015	N5-carboxyaminoimidazole ribonucleotide synthase	-	-	102	175	5.7E-31
Gene3D	G3DSA:3.30.1490.20	-	IPR013815	ATP-grasp fold, subdomain 1	102	175	8.7E-25
SUPERFAMILY	SSF51246	Rudiment single hybrid motif	IPR011054	Rudiment single hybrid motif	297	357	1.49E-13
Pfam	PF02222	ATP-grasp domain	IPR003135	ATP-grasp fold, ATP-dependent carboxylate-amine ligase-type	106	272	7.3E-56
Hamap	MF_01928	N5-carboxyaminoimidazole ribonucleotide synthase [purK].	IPR005875	Phosphoribosylaminoimidazole carboxylase, ATPase subunit	2	344	39.047749
Gene3D	G3DSA:3.30.470.20	-	-	-	176	361	4.7E-61
PANTHER	PTHR11609	PURINE BIOSYNTHESIS PROTEIN 6/7, PUR6/7	-	-	2	355	7.0E-108
Pfam	PF17769	Phosphoribosylaminoimidazole carboxylase C-terminal domain	IPR040686	Phosphoribosylaminoimidazole carboxylase, C-terminal domain	298	349	1.5E-12
FunFam	G3DSA:3.40.50.20:FF:000016	N5-carboxyaminoimidazole ribonucleotide synthase	-	-	1	101	1.3E-47
SUPERFAMILY	SSF52440	PreATP-grasp domain	IPR016185	Pre-ATP-grasp domain superfamily	2	94	1.21E-23
Gene3D	G3DSA:3.40.50.20	-	-	-	1	101	1.6E-33
SUPERFAMILY	SSF56059	Glutathione synthetase ATP-binding domain-like	-	-	97	292	1.94E-55
NCBIfam	TIGR01161	JCVI: 5-(carboxyamino)imidazole ribonucleotide synthase	IPR005875	Phosphoribosylaminoimidazole carboxylase, ATPase subunit	2	348	1.9E-108

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.