Pseudomonas putida BIRD-1, PPUBIRD1_4915 (mutM)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0003676 nucleic acid binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF46946
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008270 zinc ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01149
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006284 base-excision repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01149
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003684 damaged DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06831
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF06831
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01149
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0019104 DNA N-glycosylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF01149
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00577
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00577
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG ppb03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_00103 Formamidopyrimidine-DNA glycosylase [mutM]. IPR020629 Formamidopyrimidine-DNA glycosylase 1 270 44.464748
Pfam PF01149 Formamidopyrimidine-DNA glycosylase N-terminal domain IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain 1 115 3.4E-33
FunFam G3DSA:1.10.8.50:FF:000003 Formamidopyrimidine-DNA glycosylase - - 132 270 1.6E-49
SMART SM00898 Fapy_DNA_glyco_2 IPR012319 Formamidopyrimidine-DNA glycosylase, catalytic domain 2 116 4.9E-54
PANTHER PTHR22993 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE - - 1 270 1.7E-44
SUPERFAMILY SSF57716 Glucocorticoid receptor-like (DNA-binding domain) - - 218 269 2.08E-17
SMART SM01232 H2TH_2 IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding 130 222 1.1E-43
SUPERFAMILY SSF81624 N-terminal domain of MutM-like DNA repair proteins IPR035937 MutM-like, N-terminal 2 135 5.49E-40
CDD cd08966 EcFpg-like_N - - 2 117 1.56916E-43
Gene3D G3DSA:1.10.8.50 - - - 132 270 1.2E-43
Gene3D G3DSA:3.20.190.10 - IPR035937 MutM-like, N-terminal 2 128 1.1E-39
Pfam PF06831 Formamidopyrimidine-DNA glycosylase H2TH domain IPR015886 DNA glycosylase/AP lyase, H2TH DNA-binding 130 220 8.4E-23
SUPERFAMILY SSF46946 S13-like H2TH domain IPR010979 Small ribosomal subunit protein uS13-like, H2TH 131 222 1.03E-26
NCBIfam TIGR00577 JCVI: DNA-formamidopyrimidine glycosylase IPR020629 Formamidopyrimidine-DNA glycosylase 1 269 9.7E-90
FunFam G3DSA:3.20.190.10:FF:000001 Formamidopyrimidine-DNA glycosylase - - 2 129 4.9E-47
Pfam PF06827 Zinc finger found in FPG and IleRS IPR010663 Zinc finger, FPG/IleRS-type 242 269 2.8E-9

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.