Pseudomonas aeruginosa UCBPP-PA14, PA14_05310 (gshB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004363 glutathione synthase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01380
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.30.1490.20
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006750 glutathione biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01380
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class
Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00270 Cysteine and methionine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00480 Glutathione metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.30.470.20:FF:000010 Glutathione synthetase - - 188 301 1.1E-52
SUPERFAMILY SSF52440 PreATP-grasp domain IPR016185 Pre-ATP-grasp domain superfamily 3 123 1.29E-42
Gene3D G3DSA:3.30.470.20 - - - 116 301 3.3E-128
Hamap MF_00162 Glutathione synthetase [gshB]. IPR006284 Glutathione synthetase, prokaryotic 1 317 173.70871
NCBIfam TIGR01380 JCVI: glutathione synthase IPR006284 Glutathione synthetase, prokaryotic 4 313 0.0
Gene3D G3DSA:3.30.1490.20 - IPR013815 ATP-grasp fold, subdomain 1 138 202 3.3E-128
FunFam G3DSA:3.40.50.20:FF:000009 Glutathione synthetase - - 8 116 4.0E-47
Gene3D G3DSA:3.40.50.20 - - - 8 302 3.3E-128
PANTHER PTHR21621 RIBOSOMAL PROTEIN S6 MODIFICATION PROTEIN - - 1 314 1.0E-56
Pfam PF02951 Prokaryotic glutathione synthetase, N-terminal domain IPR004215 Prokaryotic glutathione synthetase, N-terminal 4 121 2.1E-44
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like - - 124 311 2.83E-57
Pfam PF02955 Prokaryotic glutathione synthetase, ATP-grasp domain IPR004218 Prokaryotic glutathione synthetase, ATP-binding 125 297 5.0E-80
FunFam G3DSA:3.30.1490.20:FF:000009 Glutathione synthetase - - 138 202 2.0E-32

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.