Pseudomonas aeruginosa UCBPP-PA14, PA14_09600 (ddlA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Cellular Component GO:0005737 cytoplasm
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF039102
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008716 D-alanine-D-alanine ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF039102
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF039102
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00473 D-Alanine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01502 Vancomycin resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00550 Peptidoglycan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Pfam PF07478 D-ala D-ala ligase C-terminus IPR011095 D-alanine--D-alanine ligase, C-terminal 147 330 2.0E-51
Gene3D G3DSA:3.30.470.20 - - - 123 330 1.3E-73
Pfam PF01820 D-ala D-ala ligase N-terminus IPR011127 D-alanine--D-alanine ligase, N-terminal domain 7 123 5.7E-23
Hamap MF_00047 D-alanine--D-alanine ligase [ddl]. IPR005905 D-alanine--D-alanine ligase 6 335 35.469925
PIRSF PIRSF039102 Ddl/VanB IPR005905 D-alanine--D-alanine ligase 3 343 3.1E-98
Gene3D G3DSA:3.40.50.20 - - - 3 122 5.6E-25
Gene3D G3DSA:3.30.1490.20 - IPR013815 ATP-grasp fold, subdomain 1 148 211 1.3E-73
PANTHER PTHR23132 D-ALANINE--D-ALANINE LIGASE - - 4 344 2.4E-71
SUPERFAMILY SSF52440 PreATP-grasp domain IPR016185 Pre-ATP-grasp domain superfamily 5 132 2.49E-26
NCBIfam TIGR01205 JCVI: D-alanine--D-alanine ligase IPR005905 D-alanine--D-alanine ligase 7 331 2.3E-87
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like - - 133 334 2.65E-54

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.