Pseudomonas aeruginosa UCBPP-PA14, PA14_12060 (pbpA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0009002 serine-type D-Ala-D-Ala carboxypeptidase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Cellular Component GO:0016020 membrane
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0008658 penicillin binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03717
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0009252 peptidoglycan biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:MF_02081
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Cell wall / LPS / capsule Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01501 beta-Lactam resistance 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00550 Peptidoglycan biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
PANTHER PTHR30627 PEPTIDOGLYCAN D,D-TRANSPEPTIDASE - - 11 615 0.0
Hamap MF_02081 Peptidoglycan D,D-transpeptidase MrdA [mrdA]. IPR017790 Penicillin-binding protein 2 3 611 52.463512
Pfam PF03717 Penicillin-binding Protein dimerisation domain IPR005311 Penicillin-binding protein, dimerisation domain 64 236 4.7E-46
Gene3D G3DSA:3.40.710.10 - IPR012338 Beta-lactamase/transpeptidase-like 250 622 6.0E-105
Pfam PF00905 Penicillin binding protein transpeptidase domain IPR001460 Penicillin-binding protein, transpeptidase 268 604 1.7E-75
SUPERFAMILY SSF56519 Penicillin binding protein dimerisation domain IPR036138 Penicillin-binding protein, dimerisation domain superfamily 56 250 4.19E-53
SUPERFAMILY SSF56601 beta-lactamase/transpeptidase-like IPR012338 Beta-lactamase/transpeptidase-like 251 607 1.59E-102
NCBIfam TIGR03423 JCVI: penicillin-binding protein 2 IPR017790 Penicillin-binding protein 2 19 607 0.0
Gene3D G3DSA:3.90.1310.10 - - - 64 246 6.7E-52
Gene3D G3DSA:3.30.1390.30 - - - 85 161 6.7E-52

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.