Pseudomonas aeruginosa UCBPP-PA14, PA14_39945 (phzC2)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Feature Overview

Strain Pseudomonas aeruginosa UCBPP-PA14 (Lee et al., 2006)
GCF_000014625.1|latest
Locus Tag
PA14_39945
Name
phzC2
Replicon chromosome
Genomic location 3559479 - 3560696 (- strand)
Transposon Mutants 1 transposon mutants in UCBPP-PA14
Transposon Mutants in orthologs 7 transposon mutants in orthologs

Cross-References

RefSeq YP_791338.1
GI 116054444
Entrez 4384043
INSDC ABJ15680.1
NCBI Locus Tag PA14_39945
UniParc UPI0000E44AE1
UniProtKB Acc Q02L48
UniProtKB ID Q02L48_PSEAB
UniRef100 UniRef100_Q02L48
UniRef50 UniRef50_Q51517
UniRef90 UniRef90_B7V695

Product

Feature Type CDS
Coding Frame 1
Product Name
phenazine biosynthesis protein PhzC
Synonyms
Evidence for Translation
Charge (pH 7) 1.90
Kyte-Doolittle Hydrophobicity Value -0.253
Molecular Weight (kDa) 44.3
Isoelectric Point (pI) 7.36

Subcellular localization

Individual Mappings
Localization Confidence PMID
Cytoplasmic Class 3
Additional evidence for subcellular localization

AlphaFold 2 Protein Structure Predictions

Protein structure predictions using a neural network model developed by DeepMind. If a UniProtKB accession is associated with this protein, a search link will be provided below.

Look for predicted 3D structure in AlphaFold DB: Search

PDB 3D Structures

Accession Header Accession Date Compound Source Resolution Method Percent Identity
6BMC TRANSFERASE 11/14/17 The structure of a dimeric type II DAH7PS associated with pyocyanin biosynthesis in Pseudomonas aeruginosa Pseudomonas aeruginosa 2.7 X-RAY DIFFRACTION 99.8

Virulence Evidence

Source 1
Database PseudoCAP
Category Phenazine biosynthesis
Evidence ECO:0000316
genetic interaction evidence used in manual assertion
Host Organism Mus musculus
Notes phz2 operon, but not phz1 operon required for lung colonization in acute mouse pulmonary Infection model
Infection model acute mouse pulmonary Infection model
Reference 23129634

Pathogen Association Analysis

Results
Common
Found in both pathogen and nonpathogenic strains
Hits to this gene were found in 167 genera

Orthologs/Comparative Genomics

Pseudomonas Ortholog Database View orthologs at Pseudomonas Ortholog Database
Pseudomonas Ortholog Group POG001495 (461 members)
Putative Inparalogs None Found

Interactions

STRING database Search for predicted protein-protein interactions using:
Search term: PA14_39945
Search term: phzC2

Human Homologs

References

No references are associated with this feature.