Pseudomonas aeruginosa UCBPP-PA14, PA14_52240

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Molecular Function	GO:0000155	phosphorelay sensor kinase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00082	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0007165	signal transduction	ISM Inferred from Sequence Model Term mapped from: InterPro:cd00082	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016772	transferase activity, transferring phosphorus-containing groups	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Cellular Component	GO:0016021	integral component of membrane	ISM Inferred from Sequence Model Term mapped from: InterPro:SM00304	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0016310	phosphorylation	ISM Inferred from Sequence Model Term mapped from: InterPro:PR00344	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other UCBPP-PA14 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pau02020	Two-component system	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
PseudoCAP		Two-component System		ECO:0000037 not_recorded

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF00512	His Kinase A (phospho-acceptor) domain	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	234	291	2.3E-9
SUPERFAMILY	SSF55874		IPR036890	Histidine kinase/HSP90-like ATPase superfamily	282	443	1.7E-31
ProSiteProfiles	PS50109	Histidine kinase domain profile.	IPR005467	Histidine kinase domain	240	445	36.219
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	374	388	1.1E-6
CDD	cd06225	HAMP	IPR003660	HAMP domain	180	229	2.49227E-7
Pfam	PF02518	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	IPR003594	Histidine kinase/HSP90-like ATPase	340	431	4.8E-14
Gene3D	G3DSA:3.30.450.170		IPR038428	2-component histidine kinase, sensor domain superfamily	26	149	1.7E-42
CDD	cd00082	HisKA	IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	231	287	2.77255E-8
ProSiteProfiles	PS50885	HAMP domain profile.	IPR003660	HAMP domain	177	232	9.729
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	392	402	1.1E-6
Pfam	PF00672	HAMP domain	IPR003660	HAMP domain	174	228	1.1E-12
PRINTS	PR00344	Bacterial sensor protein C-terminal signature	IPR004358	Signal transduction histidine kinase-related protein, C-terminal	407	425	1.1E-6
SMART	SM00304		IPR003660	HAMP domain	177	232	1.7E-10
Coils	Coil				266	286	-
SMART	SM00387		IPR003594	Histidine kinase/HSP90-like ATPase	337	445	2.5E-25
SUPERFAMILY	SSF47384		IPR036097	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily	217	291	1.96E-11
Pfam	PF16750	Sensor domain of 2-component histidine kinase	IPR031930	2-component histidine kinase, sensor domain	39	148	7.7E-35
SMART	SM00388		IPR003661	Signal transduction histidine kinase, dimerisation/phosphoacceptor domain	233	292	4.5E-11
Gene3D	G3DSA:1.10.287.130				181	293	1.4E-21
SUPERFAMILY	SSF158472				177	229	4.05E-7
Gene3D	G3DSA:3.30.565.10		IPR036890	Histidine kinase/HSP90-like ATPase superfamily	320	445	1.5E-27
CDD	cd16949	HATPase_CpxA-like			342	443	9.62552E-34

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.