Pseudomonas aeruginosa UCBPP-PA14, PA14_60370 (ileS)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006428 isoleucyl-tRNA aminoacylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00392
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004822 isoleucine-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00392
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000166 nucleotide binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00392
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000049 tRNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:cd07960
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006418 tRNA aminoacylation for protein translation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00133
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00392
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0002161 aminoacyl-tRNA editing activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF50677
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004812 aminoacyl-tRNA ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00133
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Translation, post-translational modification, degradation Other UCBPP-PA14 genes in this class
Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00970 Aminoacyl-tRNA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 377 646 2.9E-66
Gene3D G3DSA:1.10.730.20 - - - 647 935 1.2E-91
PRINTS PR00984 Isoleucyl-tRNA synthetase signature IPR002301 Isoleucine-tRNA ligase 529 542 3.1E-32
SUPERFAMILY SSF50677 ValRS/IleRS/LeuRS editing domain IPR009008 Valyl/Leucyl/Isoleucyl-tRNA synthetase, editing domain 201 401 5.76E-54
PRINTS PR00984 Isoleucyl-tRNA synthetase signature IPR002301 Isoleucine-tRNA ligase 235 258 3.1E-32
FunFam G3DSA:3.40.50.620:FF:000042 Isoleucine--tRNA ligase - - 18 211 1.0E-97
Gene3D G3DSA:1.10.10.830 - - - 480 532 1.4E-5
CDD cd00818 IleRS_core - - 49 643 4.48649E-98
Gene3D G3DSA:3.40.50.620 HUPs IPR014729 Rossmann-like alpha/beta/alpha sandwich fold 16 210 8.6E-51
CDD cd07960 Anticodon_Ia_Ile_BEm IPR033708 Isoleucyl tRNA synthetase type 1, anticodon-binding domain 646 826 6.01315E-83
Pfam PF00133 tRNA synthetases class I (I, L, M and V) IPR002300 Aminoacyl-tRNA synthetase, class Ia 28 646 0.0
PRINTS PR00984 Isoleucyl-tRNA synthetase signature IPR002301 Isoleucine-tRNA ligase 51 62 3.1E-32
PRINTS PR00984 Isoleucyl-tRNA synthetase signature IPR002301 Isoleucine-tRNA ligase 399 414 3.1E-32
Pfam PF08264 Anticodon-binding domain of tRNA ligase IPR013155 Methionyl/Valyl/Leucyl/Isoleucyl-tRNA synthetase, anticodon-binding 691 847 1.2E-27
PRINTS PR00984 Isoleucyl-tRNA synthetase signature IPR002301 Isoleucine-tRNA ligase 567 576 3.1E-32
Pfam PF06827 Zinc finger found in FPG and IleRS IPR010663 Zinc finger, FPG/IleRS-type 905 931 1.0E-7
NCBIfam TIGR00392 JCVI: isoleucine--tRNA ligase IPR002301 Isoleucine-tRNA ligase 15 849 0.0
FunFam G3DSA:1.10.730.20:FF:000001 Isoleucine--tRNA ligase - - 647 935 2.7E-117
SUPERFAMILY SSF52374 Nucleotidylyl transferase - - 3 652 0.0
SUPERFAMILY SSF47323 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases IPR009080 Aminoacyl-tRNA synthetase, class Ia, anticodon-binding 658 934 1.44E-76
PANTHER PTHR42765 SOLEUCYL-TRNA SYNTHETASE - - 3 937 0.0
FunFam G3DSA:3.40.50.620:FF:000048 Isoleucine--tRNA ligase - - 377 644 3.2E-126
Hamap MF_02002 Isoleucine--tRNA ligase [ileS]. IPR023585 Isoleucine-tRNA ligase, type 1 2 934 21.17318

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.