Pseudomonas aeruginosa UCBPP-PA14, PA14_62530 (cbrA)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:1900407 regulation of cellular response to oxidative stress
IMP
Inferred from Mutant Phenotype 		ECO:0000016
loss-of-function mutant phenotype evidence		 24379284 Reviewed by curator
Biological Process GO:0009405 pathogenesis
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 24379284 Reviewed by curator
Biological Process GO:0009405 pathogenesis
IMP
Inferred from Mutant Phenotype 		ECO:0000016
loss-of-function mutant phenotype evidence		 24379284 Reviewed by curator
Biological Process GO:1900232 negative regulation of single-species biofilm formation on inanimate substrate
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4725
 ECO:0000249
sequence similarity evidence used in automatic assertion		 21169488
Biological Process GO:2000147 positive regulation of cell motility
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4725
 ECO:0000249
sequence similarity evidence used in automatic assertion		 21169488
Biological Process GO:0000160 phosphorelay signal transduction system
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4725
 ECO:0000249
sequence similarity evidence used in automatic assertion		 11401699
Biological Process GO:1900407 regulation of cellular response to oxidative stress
IMP
Inferred from Mutant Phenotype 		ECO:0000315
mutant phenotype evidence used in manual assertion		 24379284 Reviewed by curator
Biological Process GO:0016310 phosphorylation
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006355 regulation of transcription, DNA-templated
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00989
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0000155 phosphorelay sensor kinase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016772 transferase activity, transferring phosphorus-containing groups
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PR00344
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0007165 signal transduction
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SM00388
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Two-component regulatory systems Other UCBPP-PA14 genes in this class
Carbon compound catabolism Other UCBPP-PA14 genes in this class

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.30.565.10 - IPR036890 Histidine kinase/HSP90-like ATPase superfamily 823 977 7.3E-42
SUPERFAMILY SSF55785 PYP-like sensor domain (PAS domain) IPR035965 PAS domain superfamily 623 716 5.33E-9
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 902 916 2.7E-15
Gene3D G3DSA:1.10.287.130 - - - 751 819 1.3E-19
MobiDBLite mobidb-lite consensus disorder prediction - - 958 983 -
SMART SM00388 HisKA_10 IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 756 822 1.1E-10
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 920 930 2.7E-15
Pfam PF00512 His Kinase A (phospho-acceptor) domain IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 757 819 1.7E-11
Gene3D G3DSA:3.30.450.20 PAS domain - - 624 750 3.7E-9
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 933 951 2.7E-15
Gene3D G3DSA:1.20.1730.10 Sodium/glucose cotransporter IPR038377 Sodium/glucose symporter superfamily 35 519 1.7E-44
PRINTS PR00344 Bacterial sensor protein C-terminal signature IPR004358 Signal transduction histidine kinase-related protein, C-terminal 961 974 2.7E-15
Pfam PF00989 PAS fold IPR013767 PAS fold 635 718 7.7E-6
CDD cd10322 SLC5sbd - - 11 491 6.94473E-55
CDD cd00130 PAS IPR000014 PAS domain 641 738 0.0024115
PANTHER PTHR43065 SENSOR HISTIDINE KINASE - - 543 980 1.8E-70
FunFam G3DSA:1.10.287.130:FF:000022 Two-component sensor CbrA - - 748 819 6.8E-47
Pfam PF02518 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase IPR003594 Histidine kinase/HSP90-like ATPase 865 975 3.9E-23
SMART SM00387 HKATPase_4 IPR003594 Histidine kinase/HSP90-like ATPase 865 977 1.2E-36
SUPERFAMILY SSF55874 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase IPR036890 Histidine kinase/HSP90-like ATPase superfamily 817 978 2.23E-40
SUPERFAMILY SSF47384 Homodimeric domain of signal transducing histidine kinase IPR036097 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain superfamily 750 819 1.79E-10
CDD cd00082 HisKA IPR003661 Signal transduction histidine kinase, dimerisation/phosphoacceptor domain 754 817 1.29099E-11
SMART SM00091 pas_2 IPR000014 PAS domain 632 700 3.2E-4
NCBIfam TIGR00229 JCVI: PAS domain S-box protein IPR000014 PAS domain 633 748 2.0E-8

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.