Pseudomonas aeruginosa UCBPP-PA14, PA14_62910 (carB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0071230 cellular response to amino acid stimulus
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4756
 ECO:0000249
sequence similarity evidence used in automatic assertion		 8169201
Biological Process GO:0006536 glutamate metabolic process
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4756
 ECO:0000249
sequence similarity evidence used in automatic assertion		 6402363
Molecular Function GO:0004088 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA4756
 ECO:0000249
sequence similarity evidence used in automatic assertion		 6402363
Molecular Function GO:0005524 ATP binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF02786
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006807 nitrogen compound metabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01369
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Nucleotide biosynthesis and metabolism Other UCBPP-PA14 genes in this class
Amino acid biosynthesis and metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00250 Alanine, aspartate and glutamate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00240 Pyrimidine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.30.1490.20:FF:000001 Carbamoyl-phosphate synthase large chain - - 686 755 1.3E-26
Gene3D G3DSA:3.30.470.20 - - - 665 935 8.0E-120
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like - - 128 401 1.94E-109
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 239 256 4.0E-66
SUPERFAMILY SSF52335 Methylglyoxal synthase-like IPR036914 Methylglyoxal synthase-like domain superfamily 938 1069 1.01E-39
NCBIfam TIGR01369 JCVI: carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit IPR006275 Carbamoyl-phosphate synthase, large subunit 2 1053 0.0
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 380 398 4.0E-66
PANTHER PTHR11405 CARBAMOYLTRANSFERASE FAMILY MEMBER - - 6 1061 0.0
FunFam G3DSA:1.10.1030.10:FF:000002 Carbamoyl-phosphate synthase large chain - - 405 553 1.7E-58
FunFam G3DSA:3.30.470.20:FF:000007 Carbamoyl-phosphate synthase large chain - - 119 403 0.0
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 204 223 4.0E-66
SUPERFAMILY SSF52440 PreATP-grasp domain IPR016185 Pre-ATP-grasp domain superfamily 1 127 2.01E-49
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 48 58 4.0E-66
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 297 326 4.0E-66
Gene3D G3DSA:1.10.1030.10 - IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily 404 553 1.2E-54
Gene3D G3DSA:3.40.50.20 - - - 1 116 8.7E-49
FunFam G3DSA:3.40.50.1380:FF:000004 Carbamoyl-phosphate synthase large chain - - 936 1072 2.5E-63
CDD cd01424 MGS_CPS_II IPR033937 Carbamoyl-phosphate synthase large chain, methylglyoxal synthase-like domain 942 1051 9.32562E-50
SUPERFAMILY SSF52440 PreATP-grasp domain IPR016185 Pre-ATP-grasp domain superfamily 557 675 2.3E-49
Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 673 875 1.1E-32
Gene3D G3DSA:3.40.50.1380 - IPR036914 Methylglyoxal synthase-like domain superfamily 936 1072 1.6E-42
Pfam PF02787 Carbamoyl-phosphate synthetase large chain, oligomerisation domain IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain 427 505 1.8E-25
Gene3D G3DSA:3.30.470.20 - - - 119 403 0.0
Pfam PF02786 Carbamoyl-phosphate synthase L chain, ATP binding domain IPR005479 Carbamoyl-phosphate synthetase large subunit-like, ATP-binding domain 128 334 1.6E-72
SUPERFAMILY SSF56059 Glutathione synthetase ATP-binding domain-like - - 673 933 6.72E-102
Gene3D G3DSA:3.40.50.20 - - - 554 662 5.6E-51
FunFam G3DSA:3.30.470.20:FF:000013 Carbamoyl-phosphate synthase large chain - - 665 935 0.0
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 19 33 4.0E-66
PRINTS PR00098 Carbamoyl-phosphate synthase protein CPSase domain signature IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain 168 180 4.0E-66
Hamap MF_01210_B Carbamoyl-phosphate synthase large chain [carB]. IPR006275 Carbamoyl-phosphate synthase, large subunit 1 1062 13.125657
FunFam G3DSA:3.40.50.20:FF:000003 Carbamoyl-phosphate synthase large chain - - 554 662 1.2E-63
SUPERFAMILY SSF48108 Carbamoyl phosphate synthetase, large subunit connection domain IPR036897 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain superfamily 396 554 6.28E-53
SMART SM00851 MGS_2a IPR011607 Methylglyoxal synthase-like domain 955 1041 2.7E-32
SMART SM01096 CPSase_L_D3_2 IPR005480 Carbamoyl-phosphate synthetase, large subunit oligomerisation domain 424 547 6.4E-75
FunFam G3DSA:3.40.50.20:FF:000001 Carbamoyl-phosphate synthase large chain - - 1 116 2.2E-54
Pfam PF02142 MGS-like domain IPR011607 Methylglyoxal synthase-like domain 958 1041 2.0E-19
Hamap MF_01210_A Carbamoyl-phosphate synthase large chain [carB]. IPR006275 Carbamoyl-phosphate synthase, large subunit 5 1067 13.404976

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.