Pseudomonas aeruginosa UCBPP-PA14, PA14_66310 (aceF)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Biological Process | GO:0006096 | glycolytic process |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0004742 | dihydrolipoyllysine-residue acetyltransferase activity |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Cellular Component | GO:0045254 | pyruvate dehydrogenase complex |
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01348
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
||
| Molecular Function | GO:0016746 | transferase activity, transferring acyl groups |
Inferred from Sequence Model
Term mapped from: InterPro:SSF47005
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | pau00620 | Pyruvate metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pau01120 | Microbial metabolism in diverse environments | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pau01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pau00020 | Citrate cycle (TCA cycle) | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pau01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pau00010 | Glycolysis / Gluconeogenesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pau01200 | Carbon metabolism | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pau01110 | Biosynthesis of secondary metabolites | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| MobiDBLite | mobidb-lite | consensus disorder prediction | - | - | 202 | 248 | - |
| FunFam | G3DSA:4.10.320.10:FF:000003 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 247 | 292 | 9.5E-24 |
| Pfam | PF02817 | e3 binding domain | IPR004167 | Peripheral subunit-binding domain | 247 | 282 | 8.2E-15 |
| FunFam | G3DSA:3.30.559.10:FF:000004 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 302 | 547 | 1.3E-119 |
| Gene3D | G3DSA:4.10.320.10 | - | IPR036625 | E3-binding domain superfamily | 247 | 292 | 4.7E-17 |
| PANTHER | PTHR43178 | DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF PYRUVATE DEHYDROGENASE COMPLEX | - | - | 5 | 108 | 0.0 |
| SUPERFAMILY | SSF51230 | Single hybrid motif | IPR011053 | Single hybrid motif | 118 | 212 | 6.41E-23 |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 121 | 192 | 4.7E-23 |
| CDD | cd06849 | lipoyl_domain | - | - | 5 | 74 | 3.27932E-22 |
| MobiDBLite | mobidb-lite | consensus disorder prediction | - | - | 75 | 117 | - |
| Pfam | PF00364 | Biotin-requiring enzyme | IPR000089 | Biotin/lipoyl attachment | 5 | 74 | 9.9E-23 |
| NCBIfam | TIGR01348 | JCVI: dihydrolipoyllysine-residue acetyltransferase | IPR006256 | Dihydrolipoamide acetyltransferase pyruvate dehydrogenase complex | 4 | 547 | 0.0 |
| Pfam | PF00198 | 2-oxoacid dehydrogenases acyltransferase (catalytic domain) | IPR001078 | 2-oxoacid dehydrogenase acyltransferase, catalytic domain | 318 | 546 | 1.9E-76 |
| SUPERFAMILY | SSF52777 | CoA-dependent acyltransferases | - | - | 306 | 547 | 1.25E-79 |
| Gene3D | G3DSA:2.40.50.100 | - | - | - | 2 | 79 | 3.7E-25 |
| Coils | Coil | Coil | - | - | 433 | 453 | - |
| SUPERFAMILY | SSF51230 | Single hybrid motif | IPR011053 | Single hybrid motif | 4 | 93 | 4.06E-23 |
| FunFam | G3DSA:2.40.50.100:FF:000009 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 118 | 198 | 5.6E-30 |
| Gene3D | G3DSA:3.30.559.10 | - | IPR023213 | Chloramphenicol acetyltransferase-like domain superfamily | 305 | 547 | 5.7E-87 |
| Gene3D | G3DSA:2.40.50.100 | - | - | - | 120 | 198 | 2.0E-22 |
| FunFam | G3DSA:2.40.50.100:FF:000009 | Acetyltransferase component of pyruvate dehydrogenase complex | - | - | 1 | 80 | 1.7E-30 |
| SUPERFAMILY | SSF47005 | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | IPR036625 | E3-binding domain superfamily | 242 | 286 | 4.97E-12 |
| CDD | cd06849 | lipoyl_domain | - | - | 120 | 192 | 2.19733E-19 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.