Pseudomonas aeruginosa UCBPP-PA14, PA14_66680 (maeB)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
View in JBrowse

Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004470 malic enzyme activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000106
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0051287 NAD binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF03949
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PIRSF000106
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Central intermediary metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau01120 Microbial metabolism in diverse environments 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau00620 Pyruvate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.40.50.720 - - - 160 419 3.3E-80
SUPERFAMILY SSF53223 Aminoacid dehydrogenase-like, N-terminal domain IPR046346 Aminoacid dehydrogenase-like, N-terminal domain superfamily 9 160 5.47E-51
SMART SM01274 malic_2 IPR012301 Malic enzyme, N-terminal domain 17 150 2.0E-76
PANTHER PTHR43237 NADP-DEPENDENT MALIC ENZYME - - 2 409 0.0
Pfam PF00390 Malic enzyme, N-terminal domain IPR012301 Malic enzyme, N-terminal domain 19 148 1.9E-25
Gene3D G3DSA:3.40.50.10380 - IPR037062 Malic enzyme, N-terminal domain superfamily 1 159 2.6E-61
FunFam G3DSA:3.40.50.10380:FF:000003 NADP-dependent malic enzyme - - 1 159 4.3E-75
CDD cd05311 NAD_bind_2_malic_enz IPR045213 Malic enzyme, NAD-binding domain, bacterial type 162 397 2.23256E-104
SUPERFAMILY SSF51735 NAD(P)-binding Rossmann-fold domains IPR036291 NAD(P)-binding domain superfamily 162 412 1.18E-83
SMART SM00919 Malic_M_2 IPR012302 Malic enzyme, NAD-binding 162 398 0.0
FunFam G3DSA:3.40.50.720:FF:000095 NADP-dependent malic enzyme - - 160 421 6.2E-118
PIRSF PIRSF000106 ME IPR001891 Malic oxidoreductase 45 419 4.2E-72
Pfam PF03949 Malic enzyme, NAD binding domain IPR012302 Malic enzyme, NAD-binding 164 354 2.5E-26

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.