Pseudomonas aeruginosa UCBPP-PA14, PA14_67500 (gloA3)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0004462 lactoylglutathione lyase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5111
 ECO:0000249
sequence similarity evidence used in automatic assertion		 17513180
Biological Process GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5111
 ECO:0000249
sequence similarity evidence used in automatic assertion		 17513180
Molecular Function GO:0008270 zinc ion binding
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5111
 ECO:0000249
sequence similarity evidence used in automatic assertion		 17513180
Molecular Function GO:0004462 lactoylglutathione lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0046872 metal ion binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00068
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Central intermediary metabolism Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00620 Pyruvate metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
CDD cd07233 GlxI_Zn - - 24 165 9.25426E-86
Pfam PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily IPR004360 Glyoxalase/fosfomycin resistance/dioxygenase domain 24 164 1.5E-23
PANTHER PTHR10374 LACTOYLGLUTATHIONE LYASE GLYOXALASE I - - 4 169 1.2E-74
Gene3D G3DSA:3.10.180.10 - IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 2 169 1.5E-62
SUPERFAMILY SSF54593 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase IPR029068 Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 9 167 3.49E-37
NCBIfam TIGR00068 JCVI: lactoylglutathione lyase IPR004361 Glyoxalase I 24 168 3.8E-63

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.