Pseudomonas aeruginosa UCBPP-PA14, PA14_67990 (mutY)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0006281 DNA repair
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5147
 ECO:0000249
sequence similarity evidence used in automatic assertion		 12445642
Molecular Function GO:0016787 hydrolase activity
ISS
Inferred from Sequence or Structural Similarity
Term mapped from: PseudoCAP:PA5147
 ECO:0000249
sequence similarity evidence used in automatic assertion		 12445642
Biological Process GO:0006284 base-excision repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR42944
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0006281 DNA repair
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48150
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003677 DNA binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PF00633
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0016798 hydrolase activity, acting on glycosyl bonds
ISM
Inferred from Sequence Model
Term mapped from: InterPro:PTHR42944
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:SSF48150
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0019104 DNA N-glycosylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01084
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau03410 Base excision repair 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Gene3D G3DSA:3.90.79.10 Nucleoside Triphosphate Pyrophosphohydrolase - - 225 351 6.7E-16
NCBIfam TIGR01084 JCVI: A/G-specific adenine glycosylase IPR005760 A/G-specific adenine glycosylase MutY 6 277 2.0E-109
SMART SM00478 endo3end IPR003265 HhH-GPD domain 39 190 8.4E-50
Pfam PF00633 Helix-hairpin-helix motif IPR000445 Helix-hairpin-helix motif 99 127 1.8E-8
SUPERFAMILY SSF48150 DNA-glycosylase IPR011257 DNA glycosylase 4 224 9.11E-75
Gene3D G3DSA:1.10.1670.10 - IPR023170 Helix-hairpin-helix, base-excision DNA repair, C-terminal 10 210 7.9E-87
Gene3D G3DSA:1.10.340.30 Hypothetical protein; domain 2 - - 21 132 7.9E-87
PANTHER PTHR42944 ADENINE DNA GLYCOSYLASE IPR044298 Adenine/Thymine-DNA glycosylase 6 347 3.6E-101
CDD cd00056 ENDO3c IPR003265 HhH-GPD domain 31 188 9.3429E-43
FunFam G3DSA:1.10.340.30:FF:000002 Adenine DNA glycosylase - - 21 135 7.9E-49
Pfam PF14815 NUDIX domain IPR029119 Adenine DNA glycosylase, C-terminal 237 343 6.6E-22
CDD cd03431 DNA_Glycosylase_C IPR029119 Adenine DNA glycosylase, C-terminal 241 345 7.84366E-17
SUPERFAMILY SSF55811 Nudix IPR015797 NUDIX hydrolase-like domain superfamily 220 345 5.19E-24
Pfam PF00730 HhH-GPD superfamily base excision DNA repair protein IPR003265 HhH-GPD domain 35 168 1.2E-20

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.