Pseudomonas aeruginosa UCBPP-PA14, PA14_70240 (coaC)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Molecular Function GO:0010181 FMN binding
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004632 phosphopantothenate--cysteine ligase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0015941 pantothenate catabolic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Biological Process GO:0015937 coenzyme A biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004633 phosphopantothenoylcysteine decarboxylase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR00521
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0003824 catalytic activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:G3DSA:3.40.50.1950
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

DNA replication, recombination, modification and repair Other UCBPP-PA14 genes in this class
Biosynthesis of cofactors, prosthetic groups and carriers Other UCBPP-PA14 genes in this class

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pau00770 Pantothenate and CoA biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pau01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
Hamap MF_02225 Coenzyme A biosynthesis bifunctional protein CoaBC [coaBC]. IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC 7 398 59.552757
NCBIfam TIGR00521 JCVI: bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC IPR005252 Coenzyme A biosynthesis bifunctional protein CoaBC 6 395 0.0
Pfam PF02441 Flavoprotein IPR003382 Flavoprotein 7 179 1.7E-41
Gene3D G3DSA:3.40.50.10300 - IPR035929 CoaB-like superfamily 186 402 2.2E-74
FunFam G3DSA:3.40.50.1950:FF:000002 Coenzyme A biosynthesis bifunctional protein CoaBC - - 1 185 1.2E-101
Pfam PF04127 DNA / pantothenate metabolism flavoprotein IPR007085 DNA/pantothenate metabolism flavoprotein, C-terminal 186 370 2.5E-71
Gene3D G3DSA:3.40.50.1950 - IPR036551 Flavin prenyltransferase-like 1 185 2.6E-56
SUPERFAMILY SSF102645 CoaB-like IPR035929 CoaB-like superfamily 184 400 5.49E-76
SUPERFAMILY SSF52507 Homo-oligomeric flavin-containing Cys decarboxylases, HFCD IPR036551 Flavin prenyltransferase-like 1 179 2.35E-59
PANTHER PTHR14359 HOMO-OLIGOMERIC FLAVIN CONTAINING CYS DECARBOXYLASE FAMILY - - 6 248 1.0E-49
FunFam G3DSA:3.40.50.10300:FF:000001 Coenzyme A biosynthesis bifunctional protein CoaBC - - 185 402 2.6E-97

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.