Pseudomonas aeruginosa UCBPP-PA14, PA14_71500 (soxA)

Gene Ontology

Ontology	Accession	Term	GO Evidence	Evidence Ontology (ECO) Code	Reference	Comments
Biological Process	GO:1901053	sarcosine catabolic process	ISS Inferred from Sequence or Structural Similarity Term mapped from: PseudoCAP:PA5418	ECO:0000249 sequence similarity evidence used in automatic assertion	17951379
Molecular Function	GO:0008115	sarcosine oxidase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PIRSF037980	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Biological Process	GO:0046653	tetrahydrofolate metabolic process	ISM Inferred from Sequence Model Term mapped from: InterPro:PIRSF037980	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0016491	oxidoreductase activity	ISM Inferred from Sequence Model Term mapped from: InterPro:PF07992	ECO:0000259 match to InterPro signature evidence used in automatic assertion
Molecular Function	GO:0005515	protein binding	ISM Inferred from Sequence Model Term mapped from: InterPro:G3DSA:3.30.1360.120	ECO:0000259 match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Carbon compound catabolism Other UCBPP-PA14 genes in this class

Pathways

Database	Xref	Pathway	Version	Evidence	PMID
KEGG	pau00260	Glycine, serine and threonine metabolism	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion
KEGG	pau01100	Metabolic pathways	81.0+/01-23, Jan 17	ECO:0000249 sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis	Accession	Description	Interpro Accession	Interpro Description	Amino Acid Start	Amino Acid Stop	E-value
Pfam	PF01571	Aminomethyltransferase folate-binding domain	IPR006222	Aminomethyltransferase, folate-binding domain	619	884	1.4E-74
Gene3D	G3DSA:3.30.1360.120	Probable tRNA modification gtpase trme; domain 1	IPR027266	GTP-binding protein TrmE/Aminomethyltransferase GcvT, domain 1	614	1004	3.2E-129
PRINTS	PR00469	Pyridine nucleotide disulphide reductase class-II signature	-	-	284	292	2.8E-10
PRINTS	PR00469	Pyridine nucleotide disulphide reductase class-II signature	-	-	172	194	2.8E-10
SUPERFAMILY	SSF51905	FAD/NAD(P)-binding domain	IPR036188	FAD/NAD(P)-binding domain superfamily	167	448	1.1E-33
FunFam	G3DSA:3.30.1360.120:FF:000038	Sarcosine oxidase subunit alpha	-	-	614	1004	0.0
PIRSF	PIRSF037980	Sarcos_oxid_alpha	IPR006277	Sarcosine oxidase, alpha subunit	1	1004	0.0
PRINTS	PR00469	Pyridine nucleotide disulphide reductase class-II signature	-	-	459	477	2.8E-10
PANTHER	PTHR43104	L-2-HYDROXYGLUTARATE DEHYDROGENASE, MITOCHONDRIAL	-	-	1	948	1.1E-72
Pfam	PF07992	Pyridine nucleotide-disulphide oxidoreductase	IPR023753	FAD/NAD(P)-binding domain	172	434	2.9E-12
Pfam	PF08669	Glycine cleavage T-protein C-terminal barrel domain	IPR013977	Glycine cleavage T-protein, C-terminal barrel domain	910	996	1.5E-19
FunFam	G3DSA:3.50.50.60:FF:000476	Sarcosine oxidase subunit alpha	-	-	167	317	4.0E-101
Gene3D	G3DSA:3.50.50.60	-	IPR036188	FAD/NAD(P)-binding domain superfamily	167	317	8.0E-21
Pfam	PF13510	2Fe-2S iron-sulfur cluster binding domain	-	-	17	102	3.0E-22
Pfam	PF17806	Sarcosine oxidase A3 domain	IPR041117	SoxA, A3 domain	521	604	1.2E-31
PRINTS	PR00368	FAD-dependent pyridine nucleotide reductase signature	-	-	173	192	4.5E-8
Gene3D	G3DSA:3.10.20.440	-	IPR042204	2Fe-2S iron-sulfur cluster binding domain, N-terminal	10	104	6.6E-21
SUPERFAMILY	SSF103025	Folate-binding domain	-	-	613	895	1.4E-92
PRINTS	PR00368	FAD-dependent pyridine nucleotide reductase signature	-	-	283	301	4.5E-8
SUPERFAMILY	SSF101790	Aminomethyltransferase beta-barrel domain	IPR029043	Glycine cleavage T-protein/YgfZ, C-terminal	906	1003	1.16E-17
Gene3D	G3DSA:1.10.10.1100	-	IPR041854	BFD-like [2Fe-2S]-binding domain superfamily	527	585	2.6E-6
NCBIfam	TIGR01372	JCVI: sarcosine oxidase subunit alpha family protein	IPR006277	Sarcosine oxidase, alpha subunit	2	1004	0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.