Pseudomonas aeruginosa PA7, PSPA7_0792 (trpC)
Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
Gene Ontology
| Ontology | Accession | Term | GO Evidence | Evidence Ontology (ECO) Code | Reference | Comments |
|---|---|---|---|---|---|---|
| Molecular Function | GO:0004425 | indole-3-glycerol-phosphate synthase activity |
Inferred from Sequence Model
Term mapped from: InterPro:PF00218
|
ECO:0000259 match to InterPro signature evidence used in automatic assertion |
Functional Classifications Manually Assigned by PseudoCAP
|
Pathways
| Database | Xref | Pathway | Version | Evidence | PMID |
|---|---|---|---|---|---|
| KEGG | pap01100 | Metabolic pathways | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pap00400 | Phenylalanine, tyrosine and tryptophan biosynthesis | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pap01110 | Biosynthesis of secondary metabolites | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pap01230 | Biosynthesis of amino acids | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
|
| KEGG | pap01130 | Biosynthesis of antibiotics | 81.0+/01-23, Jan 17 |
ECO:0000249
sequence similarity evidence used in automatic assertion |
Functional Predictions from Interpro
| Analysis | Accession | Description | Interpro Accession | Interpro Description | Amino Acid Start | Amino Acid Stop | E-value |
|---|---|---|---|---|---|---|---|
| Hamap | MF_00134_B | Indole-3-glycerol phosphate synthase [trpC]. | IPR013798 | Indole-3-glycerol phosphate synthase domain | 5 | 265 | 36.600861 |
| SUPERFAMILY | SSF51366 | Ribulose-phoshate binding barrel | IPR011060 | Ribulose-phosphate binding barrel | 14 | 265 | 2.94E-86 |
| CDD | cd00331 | IGPS | IPR013798 | Indole-3-glycerol phosphate synthase domain | 43 | 263 | 1.59211E-113 |
| FunFam | G3DSA:3.20.20.70:FF:000024 | Indole-3-glycerol phosphate synthase | - | - | 1 | 267 | 7.9E-97 |
| Pfam | PF00218 | Indole-3-glycerol phosphate synthase | IPR013798 | Indole-3-glycerol phosphate synthase domain | 7 | 263 | 8.3E-102 |
| PANTHER | PTHR22854 | TRYPTOPHAN BIOSYNTHESIS PROTEIN | IPR045186 | Indole-3-glycerol phosphate synthase | 5 | 265 | 9.0E-86 |
| Gene3D | G3DSA:3.20.20.70 | Aldolase class I | IPR013785 | Aldolase-type TIM barrel | 1 | 270 | 1.0E-106 |
Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.