Pseudomonas aeruginosa PA7, PSPA7_4064 (ilvA1)

Cytoplasmic
Cytoplasmic Membrane
Periplasmic
Outer Membrane
Extracellular
Unknown
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Gene Ontology

Ontology Accession Term GO Evidence Evidence Ontology (ECO) Code Reference Comments
Biological Process GO:0009097 isoleucine biosynthetic process
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01124
 ECO:0000259
match to InterPro signature evidence used in automatic assertion
Molecular Function GO:0004794 L-threonine ammonia-lyase activity
ISM
Inferred from Sequence Model
Term mapped from: InterPro:TIGR01124
 ECO:0000259
match to InterPro signature evidence used in automatic assertion

Functional Classifications Manually Assigned by PseudoCAP

Pathways

Database Xref Pathway Version Evidence PMID
KEGG pap00260 Glycine, serine and threonine metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01100 Metabolic pathways 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap00290 Valine, leucine and isoleucine biosynthesis 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01200 Carbon metabolism 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01230 Biosynthesis of amino acids 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01110 Biosynthesis of secondary metabolites 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion
KEGG pap01130 Biosynthesis of antibiotics 81.0+/01-23, Jan 17 ECO:0000249
sequence similarity evidence used in automatic assertion

Functional Predictions from Interpro

Analysis Accession Description Interpro Accession Interpro Description Amino Acid Start Amino Acid Stop E-value
FunFam G3DSA:3.40.50.1100:FF:000008 L-threonine dehydratase - - 138 311 9.6E-70
Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase IPR001721 Threonine dehydratase, ACT-like domain 430 513 2.7E-25
CDD cd04906 ACT_ThrD-I_1 - - 339 423 2.09801E-40
SUPERFAMILY SSF53686 Tryptophan synthase beta subunit-like PLP-dependent enzymes IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 16 366 2.36E-103
PANTHER PTHR48078 THREONINE DEHYDRATASE, MITOCHONDRIAL-RELATED - - 24 513 0.0
CDD cd04907 ACT_ThrD-I_2 - - 434 513 3.26962E-44
Gene3D G3DSA:3.40.1020.10 Biosynthetic Threonine Deaminase; Domain 3 IPR038110 Threonine dehydratase, ACT-like domain superfamily 339 514 2.7E-71
Pfam PF00585 C-terminal regulatory domain of Threonine dehydratase IPR001721 Threonine dehydratase, ACT-like domain 330 420 1.9E-22
NCBIfam TIGR01124 JCVI: threonine ammonia-lyase, biosynthetic IPR005787 Threonine dehydratase, biosynthetic 16 513 0.0
Pfam PF00291 Pyridoxal-phosphate dependent enzyme IPR001926 Tryptophan synthase beta chain-like, PALP domain 30 317 1.5E-81
Gene3D G3DSA:3.40.50.1100 - IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 65 156 2.1E-111
Gene3D G3DSA:3.40.50.1100 - IPR036052 Tryptophan synthase beta chain-like, PALP domain superfamily 32 311 2.1E-111
FunFam G3DSA:3.40.1020.10:FF:000001 L-threonine dehydratase - - 339 515 3.5E-74
SUPERFAMILY SSF55021 ACT-like IPR045865 ACT-like domain 421 513 9.16E-27
CDD cd01562 Thr-dehyd - - 17 321 0.0

Search for additional functional domains at the NCBI CDD database website. Go to this protein's amino acid sequence and follow the link.